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  1. Dengue and severe dengue - World Health Organization

    www.who.int/news-room/fact-sheets/detail/dengue...
    • Global Burden of Dengue
    • Transmission
    • Characteristics
    • Treatment
    • Prevention and Control
    • Who Response

    The incidence of dengue has grown dramatically around the world in recent decades. A vast majority of cases are asymptomatic and hence the actual numbers of dengue cases are underreported and many cases are misclassified. One estimate indicates 390 million dengue infections per year (95% credible interval 284–528 million), of which 96 million (67–136 million) manifest clinically (with any severity of disease).1 Another study, of the prevalence of dengue, estimates that 3.9 billion people, in...

    The Aedes aegypti mosquito is the primary vector of dengue. The virus is transmitted to humans through the bites of infected female mosquitoes. After virus incubation for 4–10 days, an infected mosquito is capable of transmitting the virus for the rest of its life. Infected symptomatic or asymptomatic humans are the main carriers and multipliers of the virus, serving as a source of the virus for uninfected mosquitoes. Patients who are already infected with the dengue virus can transmit the in...

    Dengue fever is a severe, flu-like illness that affects infants, young children and adults, but seldom causes death.Dengue should be suspected when a high fever (40°C/104°F) is accompanied by 2 of the following symptoms: severe headache, pain behind the eyes, muscle and joint pains, nausea, vomiting, swollen glands or rash. Symptoms usually last for 2–7 days, after an incubation period of 4–10 days after the bite from an infected mosquito.Severe dengue is a potentially deadly complication due...

    There is no specific treatment for dengue fever.For severe dengue, medical care by physicians and nurses experienced with the effects and progression of the disease can save lives – decreasing mortality rates from more than 20% to less than 1%. Maintenance of the patient's body fluid volume is critical to severe dengue care.

    At present, the main method to control or prevent the transmission of dengue virus is to combat vector mosquitoes through: 1. preventing mosquitoes from accessing egg-laying habitats by environmental management and modification; 2. disposing of solid waste properly and removing artificial man-made habitats; 3. covering, emptying and cleaning of domestic water storage containers on a weekly basis; 4. applying appropriate insecticides to water storage outdoor containers; 5. using of personal ho...

    WHO responds to dengue in the following ways: 1. supports countries in the confirmation of outbreaks through its collaborating network of laboratories; 2. provides technical support and guidance to countries for the effective management of dengue outbreaks; 3. supports countries to improve their reporting systems and capture the true burden of the disease; 4. provides training on clinical management, diagnosis and vector control at the regional level with some of its collaborating centres; 5....

  2. Why only some people develop life-threatening dengue ...

    www.sciencedaily.com/releases/2017/01/...

    Jan 31, 2017 · Feb. 25, 2016 — Dengue fever is a mosquito-borne tropical disease that can develop into the life-threatening dengue hemorrhagic fever/dengue shock syndrome. There are currently no standard ...

  3. Mosquitoes and Hurricanes | Dengue | CDC

    www.cdc.gov/dengue/mosquito-control/mosquitoes...

    The types of mosquitoes that can spread viruses may increase 2 weeks to 2 months after a hurricane, especially in areas that did not flood but received more rainfall than usual. In areas with Aedes aegypti mosquitoes and local spread of Zika, chikungunya, or dengue, increased rainfall may result in increased hatching of Ae. aegypti eggs from ...

  4. Nov 02, 2017 · Dengue is transmitted via the bite of mosquitoes that carry the viruses. It is an unpleasant disease that can cause high fever, severe headache, and joint and muscle pain.

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  6. New antiviral mechanism for dengue therapeutics -- ScienceDaily

    www.sciencedaily.com/releases/2020/07/...

    Jan. 12, 2017 — Flaviviruses -- a family that includes Dengue, Zika and West Nile viruses -- use an unexpected mechanism to hijack the cell's machinery to replicate themselves compared to many ...

  7. Dengue | CDC - Centers for Disease Control and Prevention

    www.cdc.gov/dengue/healthcare-providers/hc...

    The World Health Organization recommends that the vaccine only be given to persons with confirmed prior dengue virus infection. The vaccine manufacturer, Sanofi Pasteur, announced in 2017 that people who receive the vaccine and have not been previously infected with a dengue virus may be at risk of developing severe dengue if they get dengue ...

  8. Dengue pathogenesis, clinical manifestation, lab diagnosis ...

    www.onlinebiologynotes.com/dengue-pathogenesis...

    Dec 08, 2017 · Dengue pathogenesis, clinical manifestation, lab diagnosis and treatment Pathogenesis of Dengue: Dengue virus after entering in the body invades the local macrophages and multiply there. Infected local cells then migrate from site of infection to lymph nodes, where monocytes and macrophages are recruited, which become targets of infection.

  9. Nov. 17, 2016 — Researchers test mechanisms explaining differences in dengue serotype and disease severity by statistically fitting mathematical models to viral load data from dengue-infected ...

  10. Virulence difference of five type I dengue viruses and the ...

    journals.plos.org/plosntds/article?id=10.1371...

    Mar 04, 2019 · Author summary Dengue is the most important vector-borne viral infection that endangers an estimated 2.5 billion people globally. The recently licensed dengue vaccine has major weaknesses and there are no antiviral drugs for the treatment of dengue related diseases. Identifying the virulence determinants is important for understanding the molecule bases of viral life cycle, also contributing ...

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