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4 days ago · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...
1 day ago · Dengue is an acute febrile illness viral infection caused by dengue virus (DENV), which is transmitted to humans through the bite of an infected Aedes mosquito 1,2,3.There are four genetically ...
Apr 10, 2024 · The study involved a comprehensive analysis of conserved regions of dengue virus serotypes 1–4's non-structural proteins (NS1, NS3, and NS5) and structural protein (E) to predict the potential B & T-cell epitopes which were linked with appropriate adjuvants and linkers to generate four distinct vaccine candidates.
Apr 17, 2024 · In this study, we explored the literature on dengue vector control methods used in high-income, city settings and associations with number of human dengue infections, and the density of mosquitoes. We found 24 papers with relevant results.
Apr 15, 2024 · Mechanism of auto-antibody production in dengue virus infection by molecular mimicry between platelets, endothelial cells and coagulatory molecules with DENV proteins Full size image It has been shown that serum from DENV-infected patients exhibit cross-reactivity with endothelial cells because auto-antibodies are induced by DENV predominantly ...
Apr 10, 2024 · These receptors respond to several viral infections, among them NOD2, a very dynamic NLR, whose role in dengue virus (DENV) infection remains unclear. This research aimed to determine the role of human NOD2 in THP-1 macrophage-like cells during DENV-2 infection.
2 days ago · With regard to heart disease, a study published in 2017 has recognized heart disease as an independent predictor of severe dengue and severe organ involvement in dengue . Mechanisms hypothesized for this these adverse manifestations are endothelial dysfunction and increased nitrous oxide contributing to the cytokine storm and increased vascular ...
