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Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.
Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...
- 10.1155/2021/4224816
- 2021
- Biomed Res Int. 2021; 2021: 4224816.
Mar 11, 2024 · In the same period, 138 (24.9%) microregions jumped from the low range to the highest (epidemic) level of dengue incidence. In the last period (2014–2020), only two (0.3%) microregions remained ...
Jan 20, 2024 · Nature Communications - Dengue virus circulation was unusually low in Brazil in 2015-2018 following the emergence of Zika virus, but subsequently resurged causing large outbreaks with a lower...
Jan 24, 2019 · Costa, V. V. et al. Dengue virus-infected dendritic cells, but not monocytes, activate natural killer cells through a contact-dependent mechanism involving adhesion molecules. mBio 8 ,...
- Ashley L St John, Ashley L St John, Abhay P S Rathore
- 2019
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Sep 30, 2021 · 1. Introduction. Dengue is a single-stranded positive-sense RNA virus, a member of the Flaviviridae family that causes dengue fever. This virus spreads through the bite of infected Aedes mosquitos [ 1 ]. Dengue fever is a major public health threat worldwide.
Nov 19, 2023 · The Life Cycle of Dengue Virus. (Dengue virus enters the host by receptor-mediated endocytosis, which subsequently results in the fusion of vesicular and viral membranes. This fusion allows the secretion of genomic RNA into the cytoplasm, which plays a role as mRNA for replication and translation.
