Search results
Oct 25, 2010 · Each year, the virus infects up to 100 million people and kills about 22,000, most of them children. To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.
Apr 23, 2024 · Most people with dengue have mild or no symptoms and will get better in 1–2 weeks. Rarely, dengue can be severe and lead to death. If symptoms occur, they usually begin 4–10 days after infection and last for 2–7 days. Symptoms may include: high fever (40°C/104°F) severe headache. pain behind the eyes.
Oct 10, 2018 · Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There are four serotypes of the virus. Each serotype is antigenically different, meaning they elicit heterologous antibodies. Infection with one serotype will create ...
Oct 31, 2019 · Dengue fever may be caused by four different serotypes: DENV1, DENV2, DENV3, or DENV4 (Kostyuchenko et al., 2013), where the immunity towards the infecting serotype is life-long; however, severe forms of the disease may occur after the second or subsequent infection caused by a different dengue virus serotype, since the cross-protection against ...
Apr 1, 2022 · Abstract. Aedes mosquitoes are implicated in the transmission of several viruses, including Dengue virus (DENV) to millions of people worldwide. The global expansion of Aedes mosquitos’ habitats creates a desperate need for control mechanisms with minimum negative effects. Deciphering the molecular interactions between DENV and its vector is ...
Interaction with specific receptor (s) at the cell surface is one of the first events in the pathogenesis of Dengue virus. However, relatively little is known about these receptors. Cellular receptors in human monocytes and mouse neural cells are main target for the viral infection. The envelope protein of the virus (E-protein) plays important ...
Nov 14, 2022 · Dengue is a mosquito-transmitted virus and the leading cause of arthropod-borne viral disease in the world. It is also known as breakbone fever due to the severity of muscle spasms and joint pain, dandy fever, or seven-day fever because of the usual duration of symptoms. Although most cases are asymptomatic, severe illness and death may occur. Aedes mosquitoes transmit the virus and are common ...
