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  1. Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

    • Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
    • 10.1007/s00284-020-02284-w
    • 2021
    • Curr Microbiol. 2021; 78(1): 17-32.
  2. Jan 24, 2019 · The existence of four different serotypes of dengue virus poses a challenge to vaccine development, as pre-existing immunity can lead to severe disease during infection with a heterologous...

    • Ashley L St John, Ashley L St John, Abhay P S Rathore
    • 2019
  3. Apr 25, 2024 · From 2009 to 2022, the FDOH reported between 19 (in 2017) to 929 (in 2022) travel-associated dengue cases per year, for a total of 2300 cases, with the majority (1815 cases, 78.9%) occurring in...

  4. Jan 15, 2023 · In this review, a few focuses on the DENV infection issues such as cross reactivity due to different serotypic DENV infection and different flavivirus infection, ADE, immune evasion and limitations of commercial diagnostic kits will be overviewed.

  5. Sep 20, 2019 · Abstract. Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus includes other arthropod borne viruses such as yellow fever virus, West Nile virus, Zika virus, tick-borne encephalitis virus.

    • Amudhan Murugesan, Mythreyee Manoharan
    • 2020
    • 10.1016/B978-0-12-819400-3.00016-8
  6. Apr 12, 2012 · Immunopathogenesis. Insights into the pathogenesis of severe dengue are hampered by the lack of an animal model that accurately recreates the transient capillary permeability syndrome accompanied...

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  8. Dec 15, 2021 · Dengue fever lasts from 3 to 7 days. Before appearing the warning signs of severe DENV infection, a slight portion of the infected patients goes to life-threatening conditions [89]. Severe DENV infection can cause organ impairment, bleeding, and plasma leakage.

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