Nov 09, 2020 · Dengue virus is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Five serotypes of the virus have been found, all of which can cause the full spectrum of disease. Nevertheless, scientists' understanding of dengue virus may be simplistic, as rather than distinct antigenic groups, a continuum appears to exist. This same study identified 47 strains of dengue virus. Additionally, coinfection with and lack of rapid tes
Nov 17, 2020 · Polymorphisms in the genes for the vitamin D receptor and FcγR seem to offer protection against severe disease in secondary dengue infection. Mechanism. When a mosquito carrying dengue virus bites a person, the virus enters the skin together with the mosquito's saliva.
Oct 28, 2020 · Introduction. Dengue is a systemic infectious disease that infects humans by the bite of an infected mosquito vector from the genus Aedes Gubler, 1998.The Dengue virus (DENV) replication cycle consists of the following steps: first, DENV enters the cell by interacting with the cell membrane via receptor-mediated endocytosis.
- Mauricio Castaño-Arcila, Luis U. Aguilera, Jesús Rodríguez-González
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Nov 16, 2020 · Flavivirus is a genus of viruses in the family Flaviviridae.This genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek virus (PCV), and Parramatta River virus (PaRV).
Nov 10, 2020 · In light of epidemiological or laboratory evidence supporting a dengue virus infection, the 1997 WHO clinical definition of dengue was defined as fever with two of the following clinical features: headache, arthralgia, retro-orbital pain, rash, myalgia, hemorrhagic manifestation or leukopenia .
Nov 04, 2020 · The glycosylation of proteins is a major protein modification that occurs extensively in eukaryotes. Glycosidases in the secretory pathway that trim N-linked glycans play key roles in protein quality control and in the specific modifications leading to mature glycoproteins. Inhibition of glucosidases in the secretory pathway is a proven therapeutic strategy, that holds great promise in the ...
Nov 01, 2020 · A disease such as dengue relies on the movement of the virus among human sub-populations as a persistence mechanism, this flow is mostly maintained by human mobility patterns (Adams and Kapan, 2009). Thus, the flow of individuals between cities can also be an important predictive factor for incidence.
6 days ago ·  This mechanism has not been shown specifically for dengue virus infection, but may occur with Ebola virus infection in vitro.  When an antibody to a virus is present for a different serotype, it is unable to neutralize the virus, which is then ingested into the cell as a sub-neutralized virus particle.
5 days ago · The abundance of viruses in the host's blood allows the host to transmit the virus to other organisms if its blood is consumed by them. When uninfected vectors become infected from feeding, they are then capable of transmitting the virus to uninfected hosts, resuming amplification of virus populations.