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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

2. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

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   Apr 22, 2024 · Dengue virus infection is known to induce endoplasmic reticulum (ER) stress, triggering signaling pathways associated with ER stress during viral infections. These pathways activate genes that support cell survival and anti-viral defenses.

3. People also ask

   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   How does a dengue virus internalize?

   • D Envelope glycoproteins attach to host receptors and form the dengue-host membrane complex, resulting in virus internalization to process its replication and propagation inside the host cell [ 13] Humans and mosquitoes are the primary hosts and vectors of DENV, respectively.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

   See all results for this question

   What is the pathogenesis of dengue infection in humans?

   • Clin Microbiol Rev. 2009 Oct; 22 (4): 564–581. Summary: Much remains to be learned about the pathogenesis of the different manifestations of dengue virus (DENV) infections in humans. They may range from subclinical infection to dengue fever, dengue hemorrhagic fever (DHF), and eventually dengue shock syndrome (DSS).

   Dengue Virus Pathogenesis: an Integrated View - PMC

   www.ncbi.nlm.nih.gov/pmc/articles/PMC2772360/

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4. www.ncbi.nlm.nih.gov › pmc › articlesDengue Virus Pathogenesis: an Integrated View - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Abstract. Summary: Much remains to be learned about the pathogenesis of the different manifestations of dengue virus (DENV) infections in humans. They may range from subclinical infection to dengue fever, dengue hemorrhagic fever (DHF), and eventually dengue shock syndrome (DSS).

   • Author: Byron E. E. Martina, Penelope Koraka, Albert D. M. E. Osterhaus
   • DOI: 10.1128/CMR.00035-09

   • Publish Year: 2009
   • Publication: Clin Microbiol Rev. 2009 Oct; 22(4): 564-581.

5. www.nature.com › articles › nri3916New insights into the immunopathology and control of dengue ...

   www.nature.com › articles › nri3916

   Abstract | Dengue virus poses a major threat to global public health: two-thirds of the world’s population is now at risk from infection by this mosquito-borne virus. Dengue virus causes

   • Author: Gavin Screaton, Juthathip Mongkolsapaya, Juthathip Mongkolsapaya, Sophie Yacoub, Sophie Yacoub, Cath...

   • Publish Year: 2015

6. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · Bleeding following dengue virus infection occurs due to multiple mechanisms including platelet activation by NS1, serotonin, and PAF, accompanied by a wide range of other coagulation abnormalities. Abstract.

7. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

8. www.sciencedirect.com › science › articleDengue virus infection – a review of pathogenesis, vaccines ...

   www.sciencedirect.com › science › article

   Jan 15, 2023 · FcR-dependent ADE is the most common mechanism for a wide range of virus infection such as HIV, influenza A, dengue and Ebola. Cells which have FcR such as monocytes, B cells, neutrophils and macrophages are easily attached by the virus-antibody complexes because the Fc region of the antibody will bind on the cell surface with FcR which leads ...