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Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.
- Fig. 1
The pathogenesis of dengue virus infection is attributed to...
- How Dengue Virus Infects Cells
Each year, the virus infects up to 100 million people and...
- Fig. 1
Sep 20, 2019 · Potential mechanisms for hepatic injury involve a variety of possible insults, including direct effects of the virus or host immune response on liver cells, circulatory compromise, and/or hypoxia due to hypotension or localized vascular leakage inside the liver capsule, hepatotoxic effects of drugs such as acetaminophen or traditional herbal ...
- Amudhan Murugesan, Mythreyee Manoharan
- 2020
- 10.1016/B978-0-12-819400-3.00016-8
Dec 15, 2021 · Dengue regards one of the utmost serious arboviral infections around the world. dengue virus (DENV) is transmitted through bites of female Aedes mosquitos especially Aedes (Stegomyia) aegypti, Ae. alpopictus [ 1 ], Ae. niveus, and Ae. polynesiensis [ 2 ].
- 10.1155/2021/4224816
- 2021
- Biomed Res Int. 2021; 2021: 4224816.
As the infected monocytes and macrophages travel through the lymphatic system, the dengue virus spreads throughout the body. During its journey, the dengue virus infects more cells, including...
Apr 22, 2024 · This review aims to summarize the complex interaction between DENV and the host cellular machinery, comprising regulatory mechanisms at various molecular levels such as epigenetic modulation of the host genome, transcription of host genes, translation of viral and host mRNAs, post-transcriptional regulation of the host transcriptome, post-transl...
Oct 2, 2023 · Previous infection with DENV increases the risk of the individual developing severe dengue. Urbanization (especially unplanned), is associated with dengue transmission through multiple social and environmental factors: population density, human mobility, access to reliable water source, water storage practice etc.
