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1. www.nih.gov › how-dengue-virus-infects-cellsHow Dengue Virus Infects Cells | National Institutes of ...

   www.nih.gov › how-dengue-virus-infects-cells

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   Oct 25, 2010 · Each year, the virus infects up to 100 million people and kills about 22,000, most of them children. To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.

   • Current Understanding of the Pathogenesis of Dengue Virus ...

     The pathogenesis of dengue virus infection is attributed to...

   • Dengue Virus - PMC - National Center for Biotechnology ...

     These counteracting mechanisms allow the virus to establish...

2. www.nature.com › scitable › topicpageHost Response to the Dengue Virus | Learn Science at Scitable

   www.nature.com › scitable › topicpage

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   The immune system is the body's primary defense against the dengue virus. When someone is infected with dengue, the innate and adaptive immune responses combine forces to fight the virus.

3. www.ncbi.nlm.nih.gov › pmc › articlesDengue virus and the host innate immune response - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Oct 10, 2018 · The main innate immune response is type I IFN and the main evasion mechanism of the virus is to target against the type I IFN response. Other innate immune responses include complement activation, apoptosis, autophagy, and RNAi.

   • Author: Naoko Uno, Ted M. Ross
   • DOI: 10.1038/s41426-018-0168-0

   • Publish Year: 2018
   • Publication: Emerg Microbes Infect. 2018; 7: 167.

4. www.nature.com › articles › nrdp201655Dengue infection | Nature Reviews Disease Primers

   www.nature.com › articles › nrdp201655

   Aug 18, 2016 · Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age. Individuals at risk of a secondary infection are...

5. www.nature.com › articles › s41577/019/0123-xAdaptive immune responses to primary and secondary dengue ...

   www.nature.com › articles › s41577/019/0123-x

   Jan 24, 2019 · Abstract. Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the circulation of multiple serotypes, global expansion of the disease and recent gains in vaccination...