A new study led by researchers at the University of California, Berkeley, finds that people who have antibodies to the mosquito-borne Zika virus are more vulnerable to developing dengue disease.
Aug 28, 2020 · Dengue and Zika virus epidemics have been lapping each other around the globe. These are closely related mosquito-borne viruses with about 40% homology within the envelope protein. We know that subsequent dengue infections bring a risk of antibody-dependent disease enhancement. Whereas emphasis has been placed on how prior dengue immunity affects Zika infection, little is known about how prior ...
About Dengue Fever: Dengue fever is spread by the female Aedes mosquito that has been infected with dengue fever virus, of which there are five strains.As many as 80% of people infected with dengue virus have no symptoms or mild fever whereas others develop more severe symptoms of dengue fever.
Mosquito-borne flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), are a growing public health concern. Systems-level analysis of how flaviviruses hijack cellular processes through virus-host protein-protein interactions (PPIs) provides information about their replication and pathogenic mechanisms.
Sep 09, 2020 · Abstract. Wolbachia-infected mosquitoes are refractory to flavivirus infections, but the role of lipids in Wolbachia-mediated virus blocking remains to be elucidated.Here, we use liquid chromatography mass spectrometry to provide a comprehensive picture of the lipidome of Aedes aegypti (Aag2) cells infected with Wolbachia only, either dengue or Zika virus only, and Wolbachia-infected Aag2 ...
Feb 06, 2020 · Dengue fever is caused by any one of four types of dengue viruses spread by mosquitoes that thrive in and near human lodgings. When a mosquito bites a person infected with a dengue virus, the virus enters the mosquito. When the infected mosquito then bites another person, the virus enters that person's bloodstream.
A pregnant woman already infected with dengue can pass the virus to her fetus during pregnancy or around the time of birth. To date, there has been one documented report of dengue spread through breast milk. Because of the benefits of breastfeeding, mothers are encouraged to breastfeed even in areas with risk of dengue. Dengue in pregnancy
Aug 15, 2018 · Mechanism that affects multiplication of dengue virus lineage is discovered August 15, 2018 By Janaína Simões | Agência FAPESP – A lineage of type 1 dengue virus found in Brazil is able to prevail over another even though it multiplies less in vector mosquitoes and infected human cells.
Dec 15, 2017 · Some serotypes of dengue virus appear to have mechanisms to slow down this process. Interferon also activates the adaptive immune system, which leads to the generation of antibodies against the virus as well as T cells that directly attack any cell infected with the virus.
The team, from the University of Texas Medical Branch, have written up their results in a study published in Proceedings of the National Academy of Sciences.The crux of the breakthrough is that the team was able to analyse and decode the co-crystal structure of the dengue capsid protein, which makes up the core of the virus, in complex with an inhibitor; understanding this structure ...