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  1. Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...

  2. Apr 23, 2024 · Most people with dengue have mild or no symptoms and will get better in 1–2 weeks. Rarely, dengue can be severe and lead to death. If symptoms occur, they usually begin 4–10 days after infection and last for 2–7 days. Symptoms may include: high fever (40°C/104°F) severe headache. pain behind the eyes.

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  4. Apr 25, 2024 · Author summary Dengue, caused by dengue virus (DENV), is the most prevalent mosquito-transmitted disease in humans and a significant public health issue worldwide. DENV nonstructural protein 1 (NS1) has been shown to contribute to dengue pathogenesis through the induction of endothelial barrier dysfunction, resulting in hyperpermeability and vascular leak–a key feature of severe dengue ...

  5. Apr 15, 2024 · A complex interaction among virulence factors, host-genes and host immune system is considered to be responsible for dengue virus (DENV) infection and disease progression. Generation of auto-antibodies during DENV infection is a major phenomenon that plays a role in the pathophysiology of dengue hemorrhagic fever and dengue shock syndrome. Hemostasis, thrombocytopenia, hepatic endothelial ...

  6. Apr 12, 2024 · What you need to know about the latest outbreak of dengue fever. Health Apr 12, 2024 2:42 PM EDT. Roughly 4.7 million people have been infected with dengue fever so far in 2024, an explosion of ...

    • Laura Santhanam
  7. May 2, 2024 · borne flavivirus consisting of serotypes DENV14 that is the causative agent of dengue disease. - Of the estimated 50-100 million dengue cases annually, 5% developseve re complications known as dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), which are characterized by severe vascular leak of fluid from the blood into tissues.

  8. 2 days ago · 9th Meeting of the Strategic and Technical Advisory Group of Experts (STAGE) for Maternal, Newborn, Child and Adolescent Health and Nutrition (MNCAHN) 13 – 15 May 2024.

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