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1. www.ncbi.nlm.nih.gov › pmc › articlesMolecular Mechanisms of Antiviral Agents against Dengue Virus

   www.ncbi.nlm.nih.gov › pmc › articles

   Mar 8, 2023 · Go to: Dengue infections are caused by the dengue virus (DENV) and transmitted by Aedes mosquitoes [ 1 ]. Presently, dengue is endemic in 100 tropical and subtropical countries in Southeast Asia, Africa, the Americas, and certain European regions [ 2 ].

   • DOI: 10.3390/v15030705
   • Published: 2023/03

   • Publication: Viruses. 2023 Mar; 15(3): 705.

2. www.drugs.com › condition › dengue-feverList of Dengue Fever Medications - Drugs.com

   www.drugs.com › condition › dengue-fever

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   Compare risks and benefits of common medications used for Dengue Fever. Find the most popular drugs, view ratings and user reviews.

3. People also ask

   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   How does a dengue virus internalize?

   • D Envelope glycoproteins attach to host receptors and form the dengue-host membrane complex, resulting in virus internalization to process its replication and propagation inside the host cell [ 13] Humans and mosquitoes are the primary hosts and vectors of DENV, respectively.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   Does a small compound inhibit dengue virus replication?

   • 180. Pambudi S., Kawashita N., Phanthanawiboon S., Omokoko M.D., Masrinoul P., Yamashita A., Limkittikul K., Yasunaga T., Takagi T., Ikuta K., et al. A small compound targeting the interaction between nonstructural proteins 2B and 3 inhibits dengue virus replication.

   Molecular Mechanisms of Antiviral Agents against Dengue Virus

   www.ncbi.nlm.nih.gov/pmc/articles/PMC10056858/

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4. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

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   Apr 22, 2024 · Addressing the various host-viral modifications at the molecular level may provide key insights into viral evolution, viral escape mechanisms, host-virus interactions, disease consequences, and public health readiness.

5. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · Dengue is a mosquito-borne Flavivirus infection, primarily transmitted by Aedes aegypti followed by Aedes albopictus mosquito and other species of genus Aedes [ 1, 4]. There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 [ 5 ].

   • Author: Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
   • DOI: 10.1007/s00284-020-02284-w

   • Publish Year: 2021
   • Publication: Curr Microbiol. 2021; 78(1): 17-32.

6. journals.plos.org › plosntds › articleDenHunt - A Comprehensive Database of the Intricate Network ...

   journals.plos.org › plosntds › article

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   Sep 12, 2016 · The ‘ Den gue Hu man I nt eraction Database’, called DenHunt, available at http://proline.biochem.iisc.ernet.in/DenHunt/ was created to catalog all interactions between dengue viral and human components published in peer-reviewed literature.

   • Author: Prashanthi Karyala, Rahul Metri, Christopher Bathula, Syam K. Yelamanchi, Lipika Sahoo, Selvam Arjun...

   • Publish Year: 2016

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8. www.nature.com › articles › s41586/021/03990-6A pan-serotype dengue virus inhibitor targeting the NS3–NS4B ...

   www.nature.com › articles › s41586/021/03990-6

   Oct 6, 2021 · Here, we describe a highly potent dengue virus inhibitor (JNJ-A07) that exerts nanomolar to picomolar activity against a panel of 21 clinical isolates that represent the natural genetic...

9. www.nature.com › articles › d41586/021/02638-9A step towards therapeutics for dengue - Nature

   www.nature.com › articles › d41586/021/02638-9

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   Oct 6, 2021 · Read the paper: A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction.