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2. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

3. www.uptodate.com › contents › dengue-virus-infectionDengue virus infection: Clinical manifestations and diagnosis

   www.uptodate.com › contents › dengue-virus-infection

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   Oct 5, 2022 · Overview — In 1997, the World Health Organization (WHO) published a classification scheme describing three categories of symptomatic DENV infection: dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS) [ 4 ]. (See 'WHO 1997 classification' below.)

4. apps.who.int › iris › bitstreamHandbook for CliniCal ManageMent of dengue

   apps.who.int › iris › bitstream

   In this section clinical manifestations and management of dengue in infants will be addressed and compared to clinical manifestations and management of dengue in older children and adults. Vertical transmission and dengue in neonates are also covered briefly. Manifestations of dengue in infants.

5. emedicine.medscape.com › article › 215840Dengue: Practice Essentials, Background, Pathophysiology

   emedicine.medscape.com › article › 215840

   Dengue is the most common and important arthropod-borne viral (arboviral) illness in humans. It is transmitted by mosquitoes of the genus Aedes, which are widely distributed in subtropical and tropical areas of the world (see the image below). [ 1, 2, 3, 4] The incidence of dengue has increased dramatically in recent decades, with estimates of ...

6. www.sciencedirect.com › science › articleDengue virus infection – a review of pathogenesis, vaccines ...

   www.sciencedirect.com › science › article

   Jan 15, 2023 · FcR-dependent ADE is the most common mechanism for a wide range of virus infection such as HIV, influenza A, dengue and Ebola. Cells which have FcR such as monocytes, B cells, neutrophils and macrophages are easily attached by the virus-antibody complexes because the Fc region of the antibody will bind on the cell surface with FcR which leads ...

7. People also ask

   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What factors are involved in the pathogenesis of dengue virus infection?

   • 1. Summary of various factors implicated in pathogenesis of dengue virus infection Higher viremia levels of DENV-2 and DENV-3 in secondary infections. Inhibits antiviral genes and enhancing the production of IL-10. Apart from various viral factors implicated in the pathogenesis of DENV infection, host genetic factors also play an important role.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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8. www.nature.com › articles › nrdp201655Dengue infection | Nature Reviews Disease Primers

   www.nature.com › articles › nrdp201655

   Aug 18, 2016 · Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age. Individuals at risk of a secondary infection...

9. iris.paho.org › bitstream › handleClinical and Laboratory Guidelines for Dengue Fever and ...

   iris.paho.org › bitstream › handle

   type (heterotypic reinfection) may trigger complex immunopathologic mechanisms leading to the two most severe manifestations of the disease: Dengue Haemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Dengue Viruses are transmitted by mosquitoes of the Aedes group. These are relatively small mosquitoes that feed exclusively in humans.