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  1. Nov 24, 2020 · There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 . A fifth serotype (DENV-5) has been detected using isolation and genetic sequence analysis in Sarawak state of Malaysia in October 2013 . The incubation period of dengue virus infection is 4–7 days.

    • Fig. 1

      The pathogenesis of dengue virus infection is attributed to...

    • An Overview

      Dengue viruses (DENVs) cause the most common arthropod-borne...

  2. Dec 15, 2021 · Naringenin (citrus flavanone) was evaluated against dengue viruses (serotypes 1–4) in Huh7.5 cells which impaired virus replication in human cells with IC 50 = 35.81, 17.97, 117.1, and 177.5 μM, respectively . Annona muricata aqueous leave extract was evaluated against dengue

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  3. Fig. 1. Complex interplay of viral and host factors in pathogenesis of dengue virus infection. pathway, targeting liver cells which leads to the stimula-tion of inflammatory cytokines. This subsequently leads to plasma leakage and accumulation of fluid in third space, ultimately causing dengue shock syndrome [30].

    • 1MB
    • Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
    • 16
    • 2021
  4. doi:10.1038/nri3916. Dengue is a positive-sense RNA virus belonging to the Flaviviridae family. There are four distinct serotypes — dengue virus serotype 1 (DENV1) to DENV4 — and several ...

    • Gavin Screaton, Juthathip Mongkolsapaya, Juthathip Mongkolsapaya, Sophie Yacoub, Sophie Yacoub, Cath...
    • 2015
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  6. Dengue is the most common mosquito-borne viral infection and was listed as one of the top 10 threats to global health by the World Health Organization (WHO) in 2019i. Half of the global pop-ulation is at risk of infection with dengue virus (DENV), resulting in 390 million infections annually [1].

  7. Dengue Pathogenesis. Dengue infections are caused by four di fferent, antigenically related serotypes (DENV-1, -2, -3, and -4). The severity of DENV infection among the four serotypes is associated with several factors. In 2009, WHO released a clarity note on the clinical diagnosis of DENV, based. Figure 1.

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