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  1. May 14, 2024 · Dengue is defined by a combination of ≥2 clinical findings in a febrile person who lives in or traveled to (in the last 14 days) a dengue-endemic area. Clinical findings include nausea, vomiting, rash, aches and pains, a positive tourniquet test, leukopenia, or any warning sign.

  2. Apr 24, 2024 · In the case of dengue virus (DENV), an arbovirus that infects more than 100 million people each year, the situation is even more complex (4, 5). Individuals with high DENV antibody titers are protected from infection and developing severe disease (6–8).

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  4. 2 days ago · Therefore, there is a theoretical risk of severe dengue if a person with no prior dengue infection receives the vaccine and is then infected with a dengue virus in the future. Hence the requirement of a confirmed dengue infection in the past for those receiving the vaccine in the UK. Read more about second dengue infections here.

  5. May 14, 2024 · A nucleic acid amplification test (NAAT) (e.g., RT-PCR) and an IgM antibody test OR. A NS1 antigen test and an IgM detection test. A serum sample is preferred for dengue testing. Dengue virus RNA can be detected with NAAT in blood, serum, and plasma. Most of these tests identify the infecting dengue virus serotype.

  6. 6 days ago · Dengue is a mosquito-borne viral disease caused by the dengue virus, an Arbovirus (arthropod-borne virus). Also known as break bone fever, a severe form of dengue is called dengue hemorrhagic fever (DHF). The disease is transmitted via the bite of an infected female Aedes aegypti mosquito. Aedes aegypti mosquito is the main vector of dengue.

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  7. Apr 25, 2024 · Author summary Dengue, caused by dengue virus (DENV), is the most prevalent mosquito-transmitted disease in humans and a significant public health issue worldwide. DENV nonstructural protein 1 (NS1) has been shown to contribute to dengue pathogenesis through the induction of endothelial barrier dysfunction, resulting in hyperpermeability and vascular leak–a key feature of severe dengue ...

  8. Apr 25, 2024 · Defeating dengue with Wolbachia. A recent study reports the efficacy of Wolbachia -infected mosquito deployments for the control of dengue fever in Indonesia. Ashley York. Research Highlights 18 ...

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