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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · Dengue virus genome encodes for three structural proteins (C, prM (M), and E) and seven non-structural (NS) proteins (NS1, NS2a, NS2B, NS3, NS4a, NS4B, and NS5). The most important non-structural protein which has been implicated in the pathogenesis of dengue viral infections is NS1 .

2. www.ncbi.nlm.nih.gov › pmc › articlesDengue Virus - PMC - National Center for Biotechnology ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 20, 2019 · Abstract. Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus includes other arthropod borne viruses such as yellow fever virus, West Nile virus, Zika virus, tick-borne encephalitis virus.

   • Author: Amudhan Murugesan, Mythreyee Manoharan
   • Published: 2020

   • DOI: 10.1016/B978-0-12-819400-3.00016-8

3. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

   • DOI: 10.1155/2021/4224816
   • Published: 2021

   • Publication: Biomed Res Int. 2021; 2021: 4224816.

4. cdnsciencepub.com › doi › fullDengue virus: epidemiology, biology, and disease aetiology

   cdnsciencepub.com › doi › full

   Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions. A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes mosquitoes. It has four antigenically distinct ...

   • Author: Sudipta Kumar Roy, Soumen Bhattacharjee

   • Publish Year: 2021

5. People also ask

   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

   See all results for this question

   How does a dengue virus infect a host cell?

   • After infecting a host cell, the dengue virus hijacks the host cell's machinery to replicate the viral RNA genome and viral proteins. Newly synthesized dengue viruses can go on to infect other host cells.

   Dengue virus structure | Learn Science at Scitable

   www.nature.com/scitable/content/dengue-virus-structure-22401481/

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6. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · Dengue typically manifests with high fever ( dengue fever ), headache, myalgia, and arthralgia, which coincide with the viremic phase [ 8 ]. After 3–6 days the patients may recover from dengue or progress to the critical phase which manifests by plasma leakage, bleeding, and organ dysfunction [ 8 ].

7. www.nature.com › scitable › topicpageDengue Viruses | Learn Science at Scitable - Nature

   www.nature.com › scitable › topicpage

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   The dengue virus attaches to the surface of a host cell and enters the cell by a process called endocytosis. Once deep inside the cell, the virus fuses with the endosomal membrane...

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     Life Cycle of the Dengue Fever Virus — HHMI BioInteractive Video

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9. www.nature.com › scitable › contentDengue virus structure | Learn Science at Scitable

   www.nature.com › scitable › content

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   Like other viruses, the dengue virus is a microscopic structure that can only replicate inside a host organism. The four closely related dengue viruses — DEN-1, DEN-2, DEN-3, and DEN-4 — are ...