Search results
People also ask
What mechanisms of action are employed by antiviral agents against DENV?
Which proteins are involved in the pathogenesis of dengue virus?
Which cytokines are involved in the pathogenesis of severe dengue?
Nov 24, 2020 · The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.
- Figure - PMC - National Center for Biotechnology Information
The pathogenesis of dengue virus infection is attributed to...
- Molecular Mechanisms of Antiviral Agents against Dengue Virus
Antiviral agents designed based on these molecular...
- Molecular mechanism of pathogenesis of dengue virus: Entry ...
Interaction with specific receptor (s) at the cell surface...
- Figure - PMC - National Center for Biotechnology Information
Nov 19, 2023 · The Life Cycle of Dengue Virus. (Dengue virus enters the host by receptor-mediated endocytosis, which subsequently results in the fusion of vesicular and viral membranes. This fusion allows the secretion of genomic RNA into the cytoplasm, which plays a role as mRNA for replication and translation.
Oct 6, 2021 · A compound called JNJ-A07 displays promising activity against dengue virus in mouse models of infection. ... NS4B through a potentially different mechanism from that ... mechanism of action, and ...
- Scott B. Biering, Eva Harris
- 2021
Jan 20, 2024 · 09 February 2023. Introduction. Dengue (DENV) is a virus that poses a serious threat to global health as the etiological agent of dengue fever. Four distinct serotypes have been reported (DENV-1...
Mar 8, 2023 · This review discusses the mechanisms of action employed by various antiviral agents against DENV. The development of host-directed antivirals targeting host receptors and direct-acting antivirals targeting DENV structural and non-structural proteins are reviewed.