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  1. Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

  2. Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions. A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes ...

    • Sudipta Kumar Roy, Soumen Bhattacharjee
    • 2021
  3. Dec 15, 2021 · Naringenin (citrus flavanone) was evaluated against dengue viruses (serotypes 1–4) in Huh7.5 cells which impaired virus replication in human cells with IC 50 = 35.81, 17.97, 117.1, and 177.5 μM, respectively . Annona muricata aqueous leave extract was evaluated against dengue

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  4. Sep 20, 2019 · Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus includes other arthropod borne viruses such as yellow fever virus, West Nile virus, Zika virus, tick-borne encephalitis virus. It infects ~50–200 million people ...

    • Amudhan Murugesan, Mythreyee Manoharan
    • 2020
    • 10.1016/B978-0-12-819400-3.00016-8
  5. The dengue virus is a tiny structure that can only replicate inside a host organism. The four closely related dengue viruses — DEN-1, DEN-2, DEN-3, and DEN-4 — are found in the same regions of ...

  6. Nov 19, 2023 · Dengue is a mosquito-borne disease that is transmitted by the bites of Aedes mosquitoes, including Aedes albopictus and Aedes aegypti.Globally, this mosquito-borne disease is regarded as the most common human arboviral infection. 1 More than 2,000 dengue-associated deaths and over 3.7 million dengue cases have already been reported from 70 countries/territories worldwide as of August 23rd ...

  7. Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...

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