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1. www.ncbi.nlm.nih.gov › pmc › articlesMolecular Mechanisms of Antiviral Agents against Dengue Virus

   www.ncbi.nlm.nih.gov › pmc › articles

   Mar 8, 2023 · Evaluations of combinations of antiviral drugs with different mechanisms of action could also lead to the development of synergistic drug combinations for the treatment of dengue at any stage of the infection.

   • Current Trends and Limitations in Dengue Antiviral Research

     Table 1 shows a list of compounds that target the dengue...

   • Current Status of Dengue Therapeutics Research and ...

     Consequently, drugs directed at the viral targets or...

2. www.nature.com › articles › d41586/021/02638-9A step towards therapeutics for dengue - Nature

   www.nature.com › articles › d41586/021/02638-9

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   Oct 6, 2021 · An effective drug against dengue virus (DENV) is urgently needed, because this mosquito-transmitted virus represents a tremendous public-health burden, with about 3.9 billion people at risk of ...

   • Author: Scott B. Biering, Eva Harris

   • Publish Year: 2021

3. People also ask

   Could a new mechanism be used to design antiviral drugs for dengue?

   • Scientists have uncovered a new mechanism for designing antiviral drugs for dengue virus. A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

   New antiviral mechanism for dengue therapeutics -- ScienceDaily

   www.sciencedaily.com/releases/2020/07/200713165556.htm

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   What are antiviral drug targets for dengue?

   • Antiviral drug targets for dengue The viral components of dengue can be targeted effectively to develop antiviral drugs classified as viral protein targets and viral enzyme targets. Viral protein targets can be sub-classified into structural and non-structural protein targets.

   Dengue structural proteins as antiviral drug targets: Current status in

   www.sciencedirect.com/science/article/pii/S0223523421003767

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   Which drugs are used in clinical trials for dengue?

   • The most recent proof-of-concept clinical trials for dengue have been performed using repurposed or off-patent drugs, namely chloroquine, prednisolone, balapiravir, celgosivir, and lovastatin (Table 1 ). These trials have all used the conventional double-blinded, randomized, placebo-controlled design with clearly defined primary end points.

   Current Status of Dengue Therapeutics Research and Development

   www.ncbi.nlm.nih.gov/pmc/articles/PMC5388029/

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4. www.sciencedaily.com › releases › 2020New antiviral mechanism for dengue therapeutics | ScienceDaily

   www.sciencedaily.com › releases › 2020

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   Jul 13, 2020 · Science News. from research organizations. New antiviral mechanism for dengue therapeutics. Date: July 13, 2020. Source: University of Texas Medical Branch at Galveston. Summary: Scientists...

5. www.sciencedaily.com › releases › 2021Very potent antiviral against dengue | ScienceDaily

   www.sciencedaily.com › releases › 2021

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   Oct 6, 2021 · Summary: Researchers have developed an ultrapotent inhibitor of the dengue virus, which causes the tropical disease known as dengue. The antiviral molecule is exceptionally effective against...

6. www.sciencedirect.com › science › articleDengue structural proteins as antiviral drug targets: Current ...

   www.sciencedirect.com › science › article

   Oct 5, 2021 · Structural proteins are building blocks of viruses, targeting them to weaken the virus and eventually kills it. Therefore can be a promising drug target for treating dengue viral infections. •. Envelope proteins are one of the widely studied structural proteins and are the most promising anti-dengue drug target. •.