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5 days ago · Seasonal and pandemic characteristics of dengue fever. From 2013 to 2020, a total of 95,339 cases of dengue fever were reported in investigated 337 cities in China, including 83,318 local cases ...
Sep 7, 2024 · Dengue virus is a positive-sense, single-stranded RNA virus of approximately 11 kb in length. The evolution and diversity of the virus are enhanced by the existence of four genetically similar...
Aug 30, 2024 · These findings suggest that human intestinal cells are a viable target for the dengue virus, potentially elucidating the GI symptoms observed in dengue fever and offering a new perspective on the pathogenetic mechanisms of the virus.
Sep 3, 2024 · Many repurposed drugs were originally designed to target different pathogens or disease mechanisms, which do not align well with the unique biology of the Dengue virus. For instance, chloroquine, primarily an anti-malarial drug, failed to exhibit significant antiviral activity against Dengue in clinical settings [ 44 ].
Sep 4, 2024 · Dengue viruses are the causative agents of dengue fever, dengue hemorrhagic fever, and dengue shock syndrome, which are mainly transmitted by Aedes aegypti and Aedes albopictus mosquitoes, and cost billions of dollars annually in patient treatment and mosquito control.
Sep 7, 2024 · By developing our understanding of the drivers of disease dynamics that arise in regions with a single vector transmitting a single serotype of dengue virus, we are now well positioned to begin...
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Sep 7, 2024 · Dengue virus is a positive-sense, single-stranded RNA virus of approximately 11 kb in length. The evolution and diversity of the virus are enhanced by the existence of four genetically similar but antigenically distinct serotypes, DENV-1, −2, −3, and −4, that are transmitted in both urban and sylvatic cycles 13, 14.
