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  1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

    Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

    • Fig. 1

      The pathogenesis of dengue virus infection is attributed to...

    • Dengue Virus

      Dengue virus (DENV) belongs to the family Flaviviridae,...

  2. en.wikipedia.org › wiki › Dengue_virusDengue virus - Wikipedia

    Dengue virus. Dengue virus ( DENV) is the cause of dengue fever. It is a mosquito -borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]

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  4. www.nejm.org › doi › fullDengue | New England Journal of Medicine

    Apr 12, 2012 · DOI: 10.1056/NEJMra1110265. VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a ...

  5. www.nature.com › scitable › topicpageDengue Viruses | Learn Science at Scitable - Nature

    The dengue virus is a roughly spherical structure composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell, the dengue virus ...

  6. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

    Dec 15, 2021 · Naringenin (citrus flavanone) was evaluated against dengue viruses (serotypes 1–4) in Huh7.5 cells which impaired virus replication in human cells with IC 50 = 35.81, 17.97, 117.1, and 177.5 μM, respectively . Annona muricata aqueous leave extract was evaluated against dengue

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  8. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

    Apr 5, 2024 · HLH is characterized by macrophage activation, natural killer (NK) cell dysfunction and depletion, and aberrant T cell activation leading to a cytokine storm [ 122 ]. HLH leading to severe dengue is one of the most important challenges in managing patients with dengue because it is associated with high mortality.

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