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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · Dengue virus genome encodes for three structural proteins (C, prM (M), and E) and seven non-structural (NS) proteins (NS1, NS2a, NS2B, NS3, NS4a, NS4B, and NS5). The most important non-structural protein which has been implicated in the pathogenesis of dengue viral infections is NS1 .

   • Fig. 1

     The pathogenesis of dengue virus infection is attributed to...

   • Dengue Virus

     Dengue viruses (DENVs) form dengue complex in genus...

2. www.nature.com › scitable › topicpageDengue Viruses | Learn Science at Scitable - Nature

   www.nature.com › scitable › topicpage

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   Introduction. Viruses are tiny agents that can infect a variety of living organisms, including bacteria, plants, and animals. Like other viruses, the dengue virus is a microscopic structure...

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4. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

   • DOI: 10.1155/2021/4224816
   • Published: 2021

   • Publication: Biomed Res Int. 2021; 2021: 4224816.

5. journals.sagepub.com › doi › 10Dengue Virus: Molecular Biology and Recent Developments in ...

   journals.sagepub.com › doi › 10

   Nov 19, 2023 · The Life Cycle of Dengue Virus. (Dengue virus enters the host by receptor-mediated endocytosis, which subsequently results in the fusion of vesicular and viral membranes. This fusion allows the secretion of genomic RNA into the cytoplasm, which plays a role as mRNA for replication and translation.

6. pubmed.ncbi.nlm.nih.gov › 33231723Current Understanding of the Pathogenesis of Dengue Virus ...

   pubmed.ncbi.nlm.nih.gov › 33231723

   Abstract. The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

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   What is the pathogenesis of dengue virus infection?

   • The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   pubmed.ncbi.nlm.nih.gov/33231723/

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   Which proteins are involved in the pathogenesis of dengue virus?

   • Dengue virus genome encodes for three structural proteins (C, prM (M), and E) and seven non-structural (NS) proteins (NS1, NS2a, NS2B, NS3, NS4a, NS4B, and NS5). The most important non-structural protein which has been implicated in the pathogenesis of dengue viral infections is NS1 [ 23 ].

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What are the four closely related dengue viruses?

   • The four closely related dengue viruses — DEN-1, DEN-2, DEN-3, and DEN-4 — are found in the same regions of the world. The dengue virus is a roughly spherical structure composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins.

   Dengue Viruses | Learn Science at Scitable - Nature

   www.nature.com/scitable/topicpage/dengue-viruses-22400925/

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8. www.cell.com › trends › molecular-medicineMolecular mechanisms in the pathogenesis of dengue infections

   www.cell.com › trends › molecular-medicine

   Oct 31, 2023 · Dengue NS1 antigen, cytokines such as IL-1β, TNF- α, and IL-6, lipid mediators such as platelet-activating factor (PAF), leukotrienes and prostaglandins, VEGF, chymase, tryptase, and MMP-9 are thought to contribute to endothelial dysfunction.