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Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.
- Figure - PMC - National Center for Biotechnology Information
The pathogenesis of dengue virus infection is attributed to...
- Production, Transmission, Pathogenesis, and Control of Dengue ...
Phospholipase A 2, a chemical constituent of Crotalus...
- Figure - PMC - National Center for Biotechnology Information
Aug 14, 2023 · Substantial gaps remain in the comprehensive understanding of the pathogenesis of dengue virus (DENV) infections. In large part, this limitation is related to the lack of a suitable animal model of disease [ 1 ]. Rhesus monkeys develop RNAemia and viremia similar in a pattern to humans after DENV challenge but do not develop clinical disease.
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Jul 6, 2022 · Introduction. Dengue is an infectious disease transmitted between humans by Aedes mosquitoes, especially across the tropical and subtropical latitudes afflicting ~400 million people annually, of which 100 million manifests clinically ( 1 ). Estimates by the World Health Organization (WHO) suggest that the global consequence of dengue is ...
- 10.3389/fimmu.2022.889196
- 2022
- Front Immunol. 2022; 13: 889196.
Apr 12, 2012 · DOI: 10.1056/NEJMra1110265. VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a ...
May 1, 2024 · Although higher viral loads, prolonged viremia, and an impaired type I IFN response are seen in patients who develop dengue hemorrhagic fever (DHF) or severe dengue, some studies have shown that viral loads in fact do not correlate with disease severity, and viral loads were lowest in DENV2 infection which was associated with higher risk of ...
Sep 3, 2021 · Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions. A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes mosquitoes. It has four antigenically distinct ...
