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Mar 8, 2002 · The first structure of a flavivirus has been determined by using a combination of cryoelectron microscopy and fitting of the known structure of glycoprotein E into the electron density map. The virus core, within a lipid bilayer, has a less-ordered structure than the external, icosahedral scaffold o …
Like other viruses, the dengue virus is a microscopic structure that can only replicate inside a host organism. The four closely related dengue viruses — DEN-1, DEN-2, DEN-3, and DEN-4 — are ...
Apr 4, 2009 · Dengue virus (DENV) is the causative agent of dengue fever, the most important arboviral disease of humans. Between 50 and 100 million cases are reported annually, and up to 500,000 people are admitted to hospitals with dengue hemorrhagic fever and dengue shock syndrome (Gubler, 2002, Halstead, 1988, Halstead, 2007).
Apr 14, 2022 · A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication. PLoS Pathog 11: e1004682. 10.1371/journal.ppat.1004682 [PMC free article] [Google Scholar] Zuker M. 2003. Mfold web server for nucleic acid folding and hybridization prediction.
Oct 8, 2001 · The first structure of a flavivirus has been determined by using a combination of cryoelectron microscopy and fitting of the known structure of glycoprotein E into the electron density map. The virus core, within a lipid bilayer, has a less-ordered structure than the external, icosahedral scaffold of 90 glycoprotein E dimers.
Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases. Each year, there are ∼50 million dengue infections and ∼500,000 individuals are hospitalized with ...
Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...
