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Consider an oral treatment for adults with Major Depressive Disorder. Talk to your doctor. Learn how it's different, view trial results and access resources for savings and support.
Learn the 5 types of therapy used to treat major depressive disorder. Find out how depression is treated with these 5 types of therapy.
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These antidepressants generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants. SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro). Serotonin and norepinephrine reuptake ...
- Overview
- Selective serotonin reuptake inhibitors
- SSRI side effects
- Serotonin-norepinephrine reuptake inhibitors
- SNRI side effects
- Tricyclic antidepressants
- TCA side effects
- Norepinephrine and dopamine reuptake inhibitors
- NDRI side effects
- Monoamine oxidase inhibitors
Overview
Treatment for major depressive disorder (also known as major depression, clinical depression, unipolar depression, or MDD) depends on the individual and the severity of the illness. However, doctors often discover the best results when both prescription medications, such as antidepressants, and psychotherapy are used in combination.
Currently, more than two-dozen antidepressant medications are available.
Antidepressants are successful in treating depression, but no single medication has been shown to be the most effective — it depends entirely on the patient and their individual circumstances. You’ll have to take the medication regularly for several weeks in order to see results and observe any side effects.
The typical course of treatment for depression initially begins with a prescription for a selective serotonin reuptake inhibitor (SSRI).
When the brain doesn’t make enough serotonin, or it can’t use existing serotonin correctly, the balance of chemicals in the brain may become uneven. SSRIs work to change the level of serotonin in the brain.
Specifically, SSRIs block the reabsorption of serotonin. By blocking the reabsorption, neurotransmitters may send and receive chemical messages more effectively. This is thought to increase the mood-boosting effects of serotonin and improve depression symptoms.
The most common SSRIs include:
•fluoxetine (Prozac)
•citalopram (Celexa)
The most common side effects experienced by people who use SSRIs include:
•digestive problems, including diarrhea
•nausea
•dry mouth
•restlessness
•headaches
Serotonin-norepinephrine reuptake inhibitors (SNRIs) are sometimes called dual reuptake inhibitors. They work by blocking the reuptake, or reabsorption, of serotonin and norepinephrine.
With additional serotonin and norepinephrine circulating in the brain, the brain’s chemical balance may be reset, and neurotransmitters are thought to communicate more effectively. This may improve mood and help relieve symptoms of depression.
The most commonly prescribed SNRIs include:
•venlafaxine (Effexor XR)
•desvenlafaxine (Pristiq)
•duloxetine (Cymbalta)
The most common side effects experienced by people who use SNRIs include:
•increased sweating
•increased blood pressure
•heart palpitations
•dry mouth
•fast heart rate
Tricyclic antidepressants (TCAs) were invented in the 1950s, and they were among the earliest antidepressants utilized to treat depression.
TCAs work by blocking the reabsorption of noradrenaline and serotonin. This may help the body prolong the mood-boosting benefits of the noradrenaline and serotonin it releases naturally, which can improve mood and reduce the effects of depression.
Many doctors prescribe TCAs because they’re thought to be as safe as newer medicines.
The most commonly prescribed TCAs include:
•amitriptyline (Elavil)
•imipramine (Tofranil)
Side effects from this class of antidepressants tend to be severe. Men tend to experience fewer side effects than women.
The most common side effects experienced by people who use TCAs include:
•weight gain
•dry mouth
•blurred vision
•drowsiness
Currently only one NDRI is FDA approved for depression.
•buproprion (Wellbutrin)
The most common side effects experienced by people who use NDRIs include:
•seizures, when taken at high doses
•anxiety
•hyperventilation
•nervousness
•agitation (jitteriness)
Monoamine oxidase inhibitors (MAOIs) are medications that are typically prescribed only when several other medications and treatments have failed.
MAOIs prevent the brain from breaking down the chemicals norepinephrine, serotonin, and dopamine. This allows the brain to maintain higher levels of these chemicals, which may boost mood and improve neurotransmitter communications.
The most common MAOIs include:
•phenelzine (Nardil)
•selegiline (Emsam, Eldepryl, and Deprenyl)
•tranylcypromine (Parnate)
Antidepressant Side Effects. Everyone reacts to medicines differently, but some side effects are typical. These include: Nausea. Weight gain. Trouble sleeping. Dry mouth. Blurred vision. Dizziness.
People also ask
What are the side effects of antidepressants?
What are the different types of antidepressants?
Which antidepressants have fewer side effects?
Side effects. Depression medication can cause side effects that make it hard for you to manage. Prescription cost. Affordability of medication and insurance coverage is a factor for many people.
Dec 4, 2018 · dry mouth. dizziness. loss of appetite. constipation. sexual problems such as low sex drive, erectile dysfunction, or ejaculation problems. weakness and fatigue. sweating. SNRIs can cause sexual ...
Mar 1, 2023 · In general, common side effects of antidepressants include: Upset stomach. Diarrhea. Headache. Drowsiness. Sexual dysfunction. Side effects of antidepressants are usually mild and improve with time. Talk to your provider if you experience unpleasant side effects. They may recommend adjusting your dose or trying a different medication.
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related to: depression medication list and side effectsThis Add-On May Help Adults Decrease Depression Symptoms More Than An Antidepressant Alone. Visit The Official Patient Website & Learn More About This Add-On MDD Treatment Option.
Is Your Patient Still Experiencing Depression Symptoms? There May Be More You Can Do. Visit The Official Physician Website & Learn More About This Add-On MDD Treatment Option.
Find Information About a Prescription Approved to Help with MDD. Read More About MDD Rx Treatment Options. Visit the Website Today for More Information.
