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  1. Dec 14, 2013 · The disease is characterized by increased capillary permeability, thrombocytopenia and coagulopathy. Thrombocytopenia with hemorrhagic manifestations warrants platelet transfusions. There is lack of evidence-based guidelines for transfusion support in patients with dengue fever.

    • Paramjit Kaur, Gagandeep Kaur
    • 10.4103/2229-516X.140708
    • 2014
    • 2014/09
  2. Dengue Management DO’s and DON’Ts. X DON’T use corticosteroids. They are not indicated and can increase the risk of GI bleeding, hyperglycemia, and immunosuppression. X DON’T give platelet transfusions for a low platelet count. Platelet transfusions do not decrease the risk of severe bleeding and may instead lead to fluid overload and ...

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    • 8
  3. Aug 12, 2022 · Patients infected with dengue often present with thrombocytopenia. In the setting of dengue, platelet transfusions as a treatment for thrombocytopenia have no clear benefits in reduction of severe bleeding or improvement of the platelet count.

    • 10.1155/2022/3358325
    • 2022
    • Case Rep Hematol. 2022; 2022: 3358325.
  4. X DON’T give platelet transfusions for a low platelet count. Platelet transfusions do not decrease the risk of severe bleeding and may instead lead to fluid overload and prolonged hospitalization. X DON’T give half normal (0.45%) saline. Half normal saline should not be given, even as a maintenance fluid, because it leaks into third

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  5. Jan 18, 2023 · Patient details (age/gender); BP, blood pressure (mmHG); PR, pulse rate; Plt, platelet count (× 10 6/ /L); Hct, hematocrit (%); WBC, white cell count (× 10 9 /L); AST (IU/L); ALT (IU/L); lactate (mmol/L); SpO 2, peripheral oxygen saturation (%); DHF, dengue hemorrhagic fever; NO, number; F, Female; M, Male; BP, Blood pressure; PR, Pulse rate ...

  6. Management of Dengue Patients. The following recommendations for management of dengue patients include sending Group A patients home with follow-up guidance and admitting Group B and Group C patients to the hospital for treatment. *Do not use prophylactic platelet transfusions.

  7. There is lack of evidence-based guidelines for transfusion support in patients with dengue fever. This contributes to inappropriate use of blood components and blood centers constantly face the challenge of inventory management during dengue outbreaks. The current review is aimed to highlight the role of platelets and other blood components in ...

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