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  1. S. aureus. infections is not recommended. There is . NO EVIDENCE. that linezolid or daptomycin are superior to TMP/SMX, doxycycline, or clindamycin for the management of skin and soft tissue infections. Linezolid or daptomycin should only be considered when the . S. aureus. isolate is resistant to other agents or the patient is intolerant of ...

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  2. Sep 16, 2022 · Staphylococcus aureus ( Staph aureus or " Staph ") is a bacterium that is carried on the skin or nasal lining of up to 30 percent of healthy individuals. In this setting, the bacteria usually cause no symptoms. However, when the skin is damaged, even with a minor injury such as a scratch or a small cut from shaving, Staph can cause a wide range ...

  3. Aug 15, 2011 · In children with minor skin infections (e.g., impetigo) or secondarily infected lesions (e.g., eczema, ulcers, lacerations), treatment with mupirocin 2% topical cream (Bactroban) is recommended ...

  4. Dec 15, 2023 · Doxycycline provides coverage for S. aureus, including MRSA; amoxicillin is added to it for streptococcal coverage. Cellulitis cure rates with TMP-SMX range from 78 to 83 percent [ 25,26 ], and support for doxycycline is based on observational data, as discussed elsewhere.

    • Commonly Used Antibiotics
    • Specific Pathogens
    • Specific Clinical Scenarios
    • Antimicrobial Stewardship
    • Pharmacokinetics & Pharmacodynamics
    • Aminoglycoside Dosing
    • Pharmacology
    • Agents
    • Spectrum
    Gentamicin synergy for endocarditis:
    General dosing strategy is shown here: .
    Administered only IV/IM.
    Excreted unchanged in the urine.
    Half-life is normally ~2.5 hours.
    Plasma protein binding is low (~5-10%).
    Gentamicin: Best gram-positive coverage.
    Tobramycin: Workhorse aminoglycoside, good gram-negative coverage.
    Amikacin: Best gram-negative coverage (often reserved for resistant pseudomonas).
    Gram-positives:
    Gram-negatives:
    Local antibiogram:
  5. Jun 18, 2019 · June 18, 2019. Evidence for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) pneumonia with trimethoprim-sulfamethoxazole (TMP-SMX), clindamycin, doxycycline, or minocycline was found to be based on limited data, according to a systematic review published in the Annals of Pharmacotherapy.

  6. Introduction. Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), first recognized in the early 1980s, was noted to occur in patients with MRSA infections who had no identifiable, predisposing risk factors. 1–5 Over time, the prevalence of CA-MRSA infection has increased across the United States in both the pediatric and adult populations with CA-MRSA infections ...

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