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Oct 24, 2017 · Traumatic brain injury (TBI) is often considered to be a risk factor for the later development of neurodegenerative conditions, but some findings do not support a link. Differences in research methods, clinical samples, and limitations encountered when assessing and documenting TBI details likely contribute to the mixed reports in the literature. Despite some variability in findings, a review ...
Mar 3, 2022 · Traumatic brain injury (TBI), particularly of greater severity (i.e., moderate-to-severe), has been identified as a risk factor for all-cause dementia and Parkinson’s disease (PD), with risk for specific dementia sub-types being more variable. Among the limited studies involving neuropathological (post-mortem) confirmation, the association ...
- Benjamin L. Brett, Raquel C. Gardner, Jonathan Godbout, Kristen Dams-O’Connor, C. Dirk Keene
- 10.1016/j.biopsych.2021.05.025
- 2021
- 2022/03/03
Sep 1, 2018 · Traumatic brain injury (TBI) was 1 of the earliest risk factors identified for Alzheimer disease and dementia. 1 Although not all studies have found an association, 2-7 most studies, including several systematic reviews and meta-analyses, 8,9 have found that moderate and severe TBI are associated with increased risk or earlier onset of ...
- Deborah E. Barnes, Deborah E. Barnes, Amy L. Byers, Amy L. Byers, Raquel C. Gardner, Raquel C. Gardn...
- 2018
The association between traumatic brain injury (TBI) and increased risk of dementia has garnered intense public and media interest in the past few years. In a newly published, comprehensive study of 164,611 patients with trauma aged ≥55 years at the time of injury, the strength of this association is explored further 1 ; the results ...
- Victoria E. Johnson, William Stewart
- 2015/03
- 10.1038/nrneurol.2014.241
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Jul 12, 2017 · This review provides an in-depth overview of diagnostic schema and risk factors influencing recovery during the acute, subacute (operationally defined as up to 3 months postinjury), and chronic injury phases across the full spectrum of individuals (e.g., athletes to neurosurgery patients) with mild traumatic brain injury (mTBI).
Sep 15, 2016 · Introduction. There is mounting epidemiological evidence that moderate or severe traumatic brain injury (TBI) is an important risk factor for neurodegenerative diseases such as Alzheimer's disease (AD) 1, 2 and Parkinson's disease (PD). 3 Relatively fewer studies have assessed the association specifically between mild TBI (MTBI) and ...
Traumatic brain injury (TBI) has the highest incidence of all common neurological disorders, and poses a substantial public health burden. TBI is increasingly documented not only as an acute condition but also as a chronic disease with long-term consequences, including an increased risk of late-onset neurodegeneration. The first Lancet Neurology Commission on TBI, published in 2017, called for ...
