taggedwiki.zubiaga.org/new_content/ec9d2cb58dd5c5f14a2f22cd93357248#:~:text=Doxycycline (INN) (pronounced /ˌdɒksɪˈsaɪkliːn/) is a member of,Inc. and marketed under the brand name Vibramycin.
- Doxycycline (INN) (pronounced /ˌdɒksɪˈsaɪkliːn/) is a member of the tetracycline antibiotics group and is commonly used to treat a variety of infections. Doxycycline is a semi-synthetic tetracycline invented and clinically developed in the early 1960s by Pfizer Inc . and marketed under the brand name Vibramycin.
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Doxycycline is a broad-spectrum tetracycline-class antibiotic used in the treatment of infections caused by bacteria and certain parasites. It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. It is also used to prevent malaria and in combination with quinine, to treat malaria.
- AU: D, US: D (Evidence of risk)
- Doryx, Doxyhexal, Doxylin among others
- Indicated Uses
- Cautions and Side Effects
- Experimental Applications
- External Links
As well as the general indications for all members of the tetracycline antibiotics group, Doxycycline is frequently used to treat chronic prostatitis, sinusitis, syphilis, chlamydia, pelvic inflammatory disease, acne and rosacea.
Cautions and side effects are similar to other members of the tetracycline antibiotic group. However the 10% risk of photosensitivity skin reactionsis of particular importance for those intending long-term use for malaria prophylaxis because it can cause permanent sensitive and thin skin. Doxycycline can cause serious depression and thoughts of suicide. Reports of GERDhave been cited with the use of doxycycline. Should not be taken with OTC(over the counter drugs) or other prescription drugs. Unlike some other members of the tetracycline group, it may be used in those with renal impairment. Previously, it was believed that doxycycline impairs the effectiveness of many types of hormonal contraception due to CYP450 induction. Recent research has shown no significant loss of effectiveness in oral contraceptives while using most tetracycline antibiotic (including doxycycline), although many physicians still recommend the use of barrier contraception for people taking the drug to prevent...
At subantimicrobial doses, doxycycline is an inhibitor of matrix metalloproteinases, and has been used in various experimental systems for this purpose; such as for recalcitrant recurrent corneal erosions. Doxycycline has been used successfully in the treatment of one patient with lymphangioleiomyomatosis, an otherwise progressive and fatal disease. Doxycyline has also been shown to attenuate cardiac hypertrophy (in mice), a deadly consequence of prolonged hypertension. Doxycycline is also used in "Tet-on" and "Tet-off" tetracycline controlled transcriptional activation to regulate transgene expression in organisms and cell cultures. Other experimental applications include: 1. Vancomycin-resistant enterococcus (VRE) 2. Infected animal bite wounds (Pasteurella multocida, Pasteurella pneumotropica) 3. Rheumatoid arthritis and reactive arthritis. 4. Chronic inflammatory lung diseases (panbronchiolitis, asthma, cystic fibrosis, bronchitis) 5. Sarcoido...
Dec 01, 2020 · Doxycycline. Generic Name: doxycycline (DOX i SYE kleen) Brand Name: Acticlate, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Oracea, Oraxyl, Periostat Targadox, Vibramycin calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs. Medically reviewed by Kaci Durbin, MD.
- Doryx, Alodox, Monodox, Oracea, Morgidox
- Tetracycline antibiotics, Miscellaneous antimalarials
doxycycline topical. Brand names: Atridox Drug class(es): mouth and throat products Doxycycline topical is used in the treatment of: Periodontitis; Multi-ingredient medications containing doxycycline: doxycycline/omega-3 polyunsaturated fatty acids systemic. Brand names: NutriDox Convenience Kit Drug class(es): tetracyclines. doxycycline ...
Doxycycline is now preferred to oxytetracycline for many of these indications because it has improved pharmacologic features. The standard dose is 250–500 mg six-hourly by mouth. In particularly severe infections, this dose may be increased accordingly.
Doxycycline is used to treat bacterial infections in many different parts of the body. It is also used to treat pimples and abscesses (usually on the face) that are caused by rosacea, also known as acne rosacea or adult acne. Doxycycline delayed-release capsules, delayed-release tablets, and tablets and Acticlate® Cap capsules are also used to prevent malaria and treat anthrax infection after possible exposure and other conditions as determined by your doctor.
They are defined as a subclass of polyketides, having an octahydrotetracene-2-carboxamide skeleton and are known as derivatives of polycyclic naphthacene carboxamide. While all tetracyclines have a common structure, they differ from each other by the presence of chloride, methyl, and hydroxyl groups.
Minocycline, sold under the brand name Minocin among others, is a tetracycline antibiotic used to treat a number of bacterial infections such as pneumonia. It is generally less preferred than the tetracycline doxycycline. It is also used for the treatment of acne and rheumatoid arthritis. It is taken by mouth or applied to the skin.