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  1. ( http://mcb.berkeley.edu/faculty/BMB/amesb.html) In addition to emphasizing the dangers of zinc deficiencies in men, and iron deficiencies in women, Dr. Ames is an advocate of supplemental alpha-lipoic acid and acetyl-L-carnitine, and supports the use of high therapeutic doses of B-vitamins.

  2. Dr. Bruce N. Ames - Micronutrients and Aging. 2/21/02 Research Interests. Tuning-up human metabolism, which varies with genetic constitution and changes with age, is likely to be a major way to minimize DNA damage, improve health and prolong healthy lifespan. The decay of mitochondria with age due to oxidation of RNA/DNA, proteins, and lipids ...

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  4. Written by: Life Extension Editorial Staff. A landmark study published in the Proceedings of the National Academy of Sciences1,2 produced by noted biochemist Bruce Ames and a team of scientists describes the powerful synergistic abilities of lipoic acid and acetyl-l-carnitine to significantly combat aging.

  5. Bruce has published more than 550 papers and is one of the few hundred most-cited scientists in all fields. On the occasion of his 90 th birthday, it is an honor to introduce this special issue dedicated to Bruce and his outstanding contributions to science and the scientific community. Bruce was born in 1928 and grew up in New York City.

    • Graham C. Walker
    • 10.1016/j.mrgentox.2019.503115
    • 2020
    • 2020/01
  6. Beagle dogs between 7.6 and 8.8 years of age administered a twice daily supplement of alpha-lipoic acid (LA) and acetyl-L-carnitine (ALC) over approximately 2 months made significantly fewer...

  7. Jan 25, 2019 · Recognizing the difference can favorably impact the health of all adults by prolonging healthy aging. Dr. Ames elucidated the differences with his Triage Theory in 2015. Unfortunately, the RDAs are mostly determined by laboratory animal growth studies and not by longevity studies.

  8. Research like this provides the first step to developing treatments that will help to improve health in later life Acetyl-L-Carnitine (ALC) is sold as an energy-booster, while Alpha-Lipoic Acid (ALA) is sold as an antioxidant with anti-aging properties.

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