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Apr 10, 2023 · Cutaneous adverse drug reactions (CADR), also known as toxidermia, are skin manifestations resulting from systemic drug administration. These reactions range from mild erythematous skin lesions to much more severe reactions such as Lyell's syndrome.
Detailed information on different types of drug rashes, including acne, exfoliative dermatitis, fixed drug eruption, hives, and more.
Feb 22, 2023 · INTRODUCTION. Classic and less common clinical presentations of cutaneous adverse reactions to drugs will be reviewed here [ 1 ]. Drug allergy, noncutaneous hypersensitivity reactions, infusion reactions, and cutaneous adverse reactions to antineoplastic drugs are discussed elsewhere. Drug hypersensitivity reactions.
Jan 12, 2023 · Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ]. It is characterized by a disseminated, and occasionally generalized, symmetric eruption of erythematous macules and/or papules ( picture 1A-B) that occur approximately one to two ...
Drugs can cause multiple skin eruptions and reactions. The most serious of these are discussed elsewhere in THE MANUAL and include Stevens-Johnson syndrome and toxic epidermal necrolysis, hypersensitivity syndrome, serum sickness, exfoliative dermatitis, angioedema, anaphylaxis, and drug-induced vasculitis.
Drug rashes are a side effect of a drug that manifests as a skin reaction. Drug rashes usually are caused by an allergic reaction to a drug, but some drug rashes are not allergic. Typical symptoms include redness, bumps, blisters, hives, itching, and sometimes peeling, or pain.
Because drugs can cause a wide variety of reactions, drugs should be considered as causes of almost any unexplained skin reaction. Base the diagnosis primarily on clinical criteria, including a detailed history of prescription and over-the-counter drugs. Stop the suspected offending drug and treat symptoms as needed.
