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Between pH 4.5 and pH 9
- In order to colonize the human gastrointestinal tract, the enteric bacterium Escherichia coli must be able to grow between pH 4.5 and pH 9 (7). Over this wide pH range, E. coli preserves enzyme activity, as well as protein and nucleic acid stability, by maintaining the cytoplasmic pH in the range from pH 7.2 to 7.8 (26, 27, 32).
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Apr 21, 2024 · Most bacteria are neutrophiles, meaning they grow optimally at a pH within one or two pH units of the neutral pH of 7 (see Figure 9.3.2 9.3. 2 ). Most familiar bacteria, like Escherichia coli, staphylococci, and Salmonella spp. are neutrophiles and do not fare well in the acidic pH of the stomach.
Mar 20, 2020 · The ability to grow at moderate acidic conditions (pH 4.0–5.0) is important to Escherichia coli colonization of the host’s intestine. Several regulatory systems are known to control acid...
- Ying Xu, Zhe Zhao, Wenhua Tong, Wenhua Tong, Yamei Ding, Bin Liu, Yixin Shi, Jichao Wang, Shenmei Su...
- 2020
Dec 1, 2023 · E. coli strains must be able to withstand a wide range of pH values (4.5–9) in order to survive and colonize the human gastrointestinal tract [49], comprising a significantly wider pH value range compared to their optimal growth pH values (6.5–7.5) [50].
Sep 24, 2020 · Figure 1. Summary of known mechanisms for responding to low pH stress in microbes. The schematic illustrates some of the better-studied mechanisms used by Gram negative (A) and Gram-positive bacteria (B) and yeasts (C) for responding to acidic conditions.
- Peter A Lund, Daniela De Biase, Oded Liran, Ott Scheler, Nuno Pereira Mira, Zeynep Cetecioglu, Estef...
- 10.3389/fmicb.2020.556140
- 2020
- Front Microbiol. 2020; 11: 556140.
Apr 5, 2011 · Key Points. Bacteria that grow optimally in a pH range of near neutral (neutralophiles) require robust mechanisms for cytoplasmic pH homeostasis in order to survive, and in some cases grow,...
Nov 11, 2005 · Most non-extremophilic bacteria grow over a broad range of external pH values, from 5.5–9.0, and maintain a cytoplasmic pH that lies within the narrow range of pH 7.4–7.8 [ 1 – 4 ]. Hence, they are able to acidify or alkalinize the cytoplasm relative to the external milieu. The consequences of being unable to do so are striking.
