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  3. www.uptodate.com › contents › evaluation-andEvaluation and management of suspected sepsis and septic ...

    Feb 13, 2024 · Empiric antibiotic therapy (first hour) — Prompt identification and treatment of the site(s) of infection is the primary therapeutic intervention, with most other interventions being purely supportive.

  4. www.ncbi.nlm.nih.gov › pmc › articlesInitial antimicrobial management of sepsis - PMC

    Aug 26, 2021 · Using a 90% minimum threshold, for infections like VAP and CLABSI, we will potentially need to recommend toxic (e.g., aminoglycoside), reserved (e.g., carbapenem), or toxic and reserved (e.g., colistin) combinations of antibiotics for almost every patient, further driving antibiotic resistance.

    • Michael S. Niederman, Rebecca M. Baron, Lila Bouadma, Thierry Calandra, Nick Daneman, Jan DeWaele, M...
    • 10.1186/s13054-021-03736-w
    • 2021
    • Crit Care. 2021; 25: 307.

  5. www.ncbi.nlm.nih.gov › books › NBK564298Escherichia coli Infection - StatPearls - NCBI Bookshelf

    Jul 13, 2023 · In general, extraintestinal infections caused by E. coli are susceptible to a variety of antibiotics, as listed below. E. coli can harbor genes for antibiotic resistance, and antibiotic therapy targeting these organisms must be tailored.

    • Matthew Mueller, Christopher R. Tainter
    • 2023/07/13

  6. med.stanford.edu › SHC-Sepsis-ABX-GuidelineSevere Sepsis and Septic Shock Antibiotic Guide

    Simple Sepsis (Community Acquired) Antibiotic A (Select one of the following) Antibiotic B (Select one of the following) +/- Antibiotic C (Select one of the following) Undifferentiated • Ceftriaxone2g IV q24h • Levofloxacin 750mg IV Q24H Pneumonia • Ceftriaxone1g IV Q24H plus Azithromycin 500mg IV q24h • Ceftriaxone 1g IV q24H plus ...

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  7. www.mayoclinic.org › diseases-conditions › e-coliE. coli - Diagnosis and treatment - Mayo Clinic

    Oct 1, 2022 · Antibiotics generally aren't recommended because they can increase the risk of serious complications and they don't appear to help treat the infection. If you have a serious E. coli infection that has caused a life-threatening form of kidney failure (hemolytic uremic syndrome), you'll be hospitalized.

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  9. www.ncbi.nlm.nih.gov › pmc › articlesConsiderations for Empiric Antimicrobial Therapy in Sepsis ...

    Aug 8, 2020 · Antibiotic therapy for sepsis can be empiric or targeted, depending on the information available at the time of initial decision. Empiric therapy is generally defined as the initial antibiotic regimen selected in the absence of definitive microbiological pathogen identification and susceptibility testing.

  10. emedicine.medscape.com › article › 217485-medicationEscherichia coli (E coli) Infections Medication - Medscape

    May 11, 2023 · In severe infection, piperacillin/tazobactam, ertapenem, or meropenem may be used. Combination therapy with antibiotics that cover E coli plus an antianaerobe can also be used (eg,...

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