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  1. Jun 12, 2020 · Abstract. Neonatal sepsis is associated with severe morbidity and mortality in the neonatal period. Clinical manifestations range from subclinical infection to severe local or systemic infection. Neonatal sepsis is divided into three groups as early-onset neonatal sepsis, late-onset neonatal sepsis and very late-onset neonatal sepsis according ...

  2. Sep 1, 2023 · The study using a sepsis calculator to assess the risk of early onset sepsis in neonates with chorioamnionitis outbreaks showed that it could reduce the risk of exposure to asymptomatic chorioamnionitis. 22, 23 Therefore, the calculator must be used cautiously to assess the diagnosis and treatment of EOS. In clinical practice, an EOS risk ...

  3. Mar 25, 2021 · Keywords: Early-onset sepsis, Early-onset sepsis risk calculator, Antibiotics, C-reactive protein, Procalcitonin Background In most high-income countries, the incidence of culture-confirmed early-onset sepsis (EOS) has decreased to 0.4–0.8 cases per 1000 live-born term infants over the last years; the overall incidence has reached about 1–2 ...

  4. Jun 19, 2019 · Neonatal sepsis may be divided into two types: early-onset neonatal sepsis (EONS) and late-onset neonatal sepsis (LONS). EONS is typically described as infection and sepsis occurring within the first 24 hours to first week of life [ 1 – 3 ]. LONS has been labeled as after 24 hours or after the first week of life, up to 28 days or 1 month [ 4 ...

  5. Jan 13, 2022 · More recently, alternative strategies have emerged, such as the use of multivariate models that include objective maternal risk factor data and the evolving newborn condition to provide a quantitative estimate of risk. 23 These models were used to develop the neonatal early-onset sepsis calculator, which provides infant-specific EOS risk ...

  6. Jan 1, 2024 · The Kaiser Permanente neonatal early-onset sepsis (EOS) calculator is an evidence-based sepsis risk assessment tool that has demonstrated potential to reduce antibiotic usage in this population. The incidence of early-onset sepsis in most HICs is 0.4–0.8 per 1000 live births.

  7. Jan 1, 2023 · Abstract. Early-onset sepsis can cause significant morbidity and mortality in newborn infants. Risk factors for sepsis include birth to mothers with inadequately treated maternal group B Streptococcus colonization, intra-amniotic infection, maternal temperature greater than 100.4°F (>38°C), rupture of membranes greater than 18 hours, and preterm labor. The organisms that most commonly cause ...

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