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  1. The tool below is intended for the use of clinicians trained and experienced in the care of newborn infants. Using this tool, the risk of early-onset sepsis can be calculated in an infant born > 34 weeks gestation. The interactive calculator produces the probability of early onset sepsis per 1000 babies by entering values for the specified ...

    • Classification

      Clinical Exam Description; Clinical Illness: Persistent need...

    • References

      Puopolo KM, Draper D, Wi S, Newman TB, Zupancic J, Lieberman...

  2. Using the CDC national incidence of early-onset sepsis of 0.5 per 1,000 live births, the calculator estimates this infant's early-onset sepsis risk to be 2.12 per 1,000 births.

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  4. The overall mortality rate of early-onset sepsis is 3 to 40% (that of early-onset GBS infection is 2 to 10%) and of late-onset sepsis is 2 to 20% (that of late-onset GBS is about 2%). Mortality in late-onset sepsis highly depends on the etiology of the infection; infections caused by gram-negative bacilli or Candida species have rates of up to ...

  5. Dec 1, 2018 · The predictive models were used to develop a Web-based Neonatal Early-Onset Sepsis Risk Calculator with recommended clinical algorithms that are based on the final risk estimate. 47 Blood culture and enhanced clinical observation are recommended for infants with an EOS risk estimated at ≥1 per 1000 live births, and blood culture and empirical ...

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018
  6. Calculate EOS risk at birth, after clinical assessment, using Neonatal Sepsis Calculator & document in the infants EMR (Done by RN) Parameters needed for EOS score calculation. Incidence of EOS: 0.5/1000 live births(CDC) (may use site incidence if available) Gestational Age (weeks and days)

  7. the first 612hours of life to estimate the risk of sepsis. Blood culture and enhanced clinical observations are recommended for infants with a risk of early onset sepsis ≥1/1000 and empirical antibiotics for infants with an estimated risk of sepsis ≥3/1000. Use of the sepsis calculator has been shown to reduce the use

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