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  1. Encephalitis lethargica is an atypical form of encephalitis. Also known as "sleeping sickness" or "sleepy sickness" (distinct from tsetse fly–transmitted sleeping sickness), it was first described in 1917 by neurologist Constantin von Economo and pathologist Jean-René Cruchet.

    • Unknown
    • Economo's disease; von Economo's encephalitis
    • Unknown
  2. Jul 14, 2017 · The chronic phase of encephalitis lethargica typically developed 1 to 5 years after the acute phase, but it could also follow immediately, or more than a decade later. One patient developed a postencephalitic syndrome 45 years after initial infection ( Sacks, 1990 ).

    • Leslie A Hoffman, Joel A Vilensky
    • 2017
  3. Nov 28, 2023 · Encephalitis lethargica is a disease characterized by: High fever. Headache. Double vision. Delayed physical and mental response. Lethargy/fatigue. In acute cases, people with the disorder may enter coma. Some also may experience: Abnormal eye movements. Upper body weakness. Muscular pains. Tremors. Neck rigidity.

  4. Feb 12, 2018 · The encephalitis lethargica epidemic of 1916-1930 is estimated to have affected at least half a million people in Europe. The disease is documented to have spread throughout the world to afflict hundreds of thousands more. The cause of the strange illness still remains a mystery today.

  5. Mar 26, 2024 · What is encephalitis lethargica? Encephalitis lethargica (EL) is a serious and rare form of encephalitis, which can present with variable and serious symptoms. It is typically seen during discrete epidemics, but sporadic cases still occur.

  6. Dec 8, 2006 · Overview. Encephalitis lethargica was a mysterious epidemic disease of the 1920s and 1930s that was better known as the “sleepy” or “sleeping” sickness. Importantly, it was associated with the subsequent development of postencephalitic parkinsonism, a condition that was popularized in Oliver Sacks’ 1973 book, Awakenings, and the 1990 ...

  7. Encephalitis lethargica (EL) is a disease characterized by high fever, headache, double vision, delayed physical and mental response, extreme tiredness (lethargy), and sometimes coma. Patients may also experience abnormal eye movements, upper body weakness, muscle pain, tremors, neck rigidity, and behavioral changes including psychosis.

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