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Aug 23, 2023 · Entamoeba coli has three distinct morphological forms: trophozoite, pre-cystic stage, and cystic stage. The most distinguishing feature is the eight-core nuclei, which develops as the cyst begins to mature.
- Akhlema Haidar, Orlando De Jesus
- 2023/08/23
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What morphological forms does Entamoeba coli have?
Does Entamoeba histolytica have a trophozoite stage?
Is Entamoeba coli pathogenic?
Trophozoites of E. coli measure 15–50 μm and have a single nucleus with irregular peripheral chromatin and a usually eccentric karyosome. The cytoplasm is often described as “dirty” and may contain vacuoles and ingested food particles, including bacteria, yeast, and even other intestinal protozoa. Cysts are 10–35 μm in diameter.
E. coli trophozoites can be distinguished by their wide and tapered pseudopodia. They are often mistaken for E. histolytica due to their overlap in size. The cysts are distinguished by noticing the eight nuclei found in the mature form. [10] To diagnose for E. coli, a stool sample is usually tested.
E. coli trophozoites stained with trichrome. Trophozoites of Entamoeba coli usually measure 15–50 µm. The trophozoites have a single nucleus with a characteristically large, eccentric karyosome and coarse, irregular peripheral chromatin.
Entamoeba histolytica virulence results from complex host–parasite interactions implicating multiple amoebic components (e.g., Gal/GalNAc lectin, cysteine proteinases, and amoebapores) and host...
Multiplication of trophozoites occurs through binary fission. Often, the newly formed trophozoites aggregate in the intestinal mucin layer and form new cysts, resulting in a self-limited and asymptomatic infection. Trophozoites may also colonize the bowel lumen as commensal flora.
Entamoeba histolytica has a feeding, replicative trophozoite stage, and a dormant cyst stage morphologically indistinguishable from the non-pathogenic E. dispar and E. moshkovskii. Differentiation may therefore not be made in routine clinical diagnosis, which traditionally relies on bright field microscopy.
