Nov 29, 2013 · This was a case of amebiasis caused by Entamoeba histolytica/dispar. Some morphologic features of the organisms in this case were not easily seen, possibly because of the medication or poor specimen preservation. Diagnostic features included: the size of the cysts, which was consistent with E. histolytica/dispar (12 to 15 micrometers).
Nov 29, 2013 · Answer to Case #70. This case showed cysts and trophozoites of Entamoeba dispar.Based on the images presented in this case study, the correct answer was Entamoaeba histolytica/dispar because E. histolytica and E. dispar cannot be distinguished based on morphologic characteristics alone, unless trophozoites with ingested red blood cells are observed.
People also ask
Where are most cases of Entamoeba histolytica found?
What was the case of amebiasis caused by an Entamoeba?
Who is the rare case of Entamoeba dispar?
Who was the first person to describe Entamoeba?
- Case Report
We report a case of E. histolytica, which is a rare parasitic infection in North America. A 66-year-old Ecuadorian female had an intermittent six-month history of bloating, explosive diarrhea and significant abdominal distension. Histopathological specimen obtained via colonoscopy revealed colitis due to E. histolytica. Diagnosis is best accomplished by the combination of serology or antigen testing together with identification of the parasite in the stool or extra-intestinal sites or histologic examination when necessary. With medical tourism and an increase of immigrants from South and Central America, disease endemic to those areas should always be considered.
Entamoeba histolytica (EH) infection of the gastrointestinal tract is common in the developing world but rare in North America. The Office of Rare Diseases (ORD) of the National Institutes of Health (NIH) considered it a rare disease. Risk factors for infection include poor sanitation, exposure to contaminated water and sexual or fecal/oral transmission . Liver abscesses are the most frequent complication of invasive amebiasis . Here, we describe a case of an intestinal infection caused by E. histolyticain Miami, FL, United States.
A 66-year-old Ecuadoran female presented for an evaluation of abdominal pain and bloody diarrhea. She has chronic colicky lower abdominal discomfort and bloating. She has had colonoscopies since 55 years of age every three years, all of which were reported as unremarkable. In February 2018 she presented to an institution in Ecuador with worsening lower abdominal pain, explosive loose stools 2-3 times daily with blood and mucus. She has no family history of inflammatory bowel disease. Computed Tomography (CT) showed a thickened colon. She underwent colonoscopy in Ecuador and was given the diagnosis of ulcerative colitis. She was started on mesalamine; the rectal bleeding stopped and bowel movements slowed to one per day. She presented to our institution in July 2018 for a second opinion due to continued intermittent colicky pains, anal discomfort, and straining. Her diarrhea resolved and she was instead experiencing intermittent constipation. She denied viral illness, antibiotic use,...
Intestinal amebiasis caused by the protozoan Entamoeba histolytica is generally asymptomatic and symptomatic patients present with dysentery and extraintestinal disease . Worldwide, approximately 50 million people are affected, with over 100,000 deaths annually . There are four species of intestinal amebae: E. histolytica, E. dispar,E. moshkovskii, andE. Bangladeshi . Most of the symptomatic disease is caused by E. histolytica, andE. dispar is generally considered nonpathogenic. Reported infections withE. moshkovskii are becoming more frequent, with increasing evidence of its potential pathogenicity. The pathogenic potential ofE. Bangladeshi remains unclear . Areas with high rates of amebic infection include India, Africa, Mexico, and parts of Central and South America. The overall prevalence of amebic infection may be as high as 50 percent in some areas . In developed countries, amebiasis is predominantly seen in travelers to endemic areas. In one prospective study o...
In summary, we report a case of E. histolyticain a developed country. Travel history or country of origin is important pieces of clinical information to obtain. Amebiasis occurs worldwide; the prevalence is disproportionately higher in developing countries because of poor socioeconomic conditions and sanitation levels. However, sporadic cases can occur in the developed countries. With medical tourism and immigration from endemic countries, amebiasis should be considered in the differential diagnosis in patients presenting with symptoms from endemic areas. Clinically amebiasis generally has a subacute onset, usually over one to three weeks. Diagnosis is best accomplished by the combination of serology or antigen testing together with identification of the parasite in the stool or extraintestinal sites (such as liver abscess pus). On rare instances, as in this case, an evaluation of the tissue biopsy is considered on a high index of suspicion and inconclusive serology or antigen testing.
- Maryam Tahir, Morgan Sendzischew Shane, R Deshpande Amar, Clara Milikowski
Recent data show that the gut microbiome plays a role in determining the clinical outcome of Entamoeba histolytica infection. We report the case of a patient who developed recurrent acute amebic colitis (second episode of acute colitis) after colonoscopy.
- Yasuaki Yanagawa, Takahiro Arisaka, Satoru Kawai, Kumiko Nakada-Tsukui, Atsuhito Fukushima, Hideyuki...
- Case Report
Amoebiasis continues to be a major cause of morbidity and mortality in children in developing countries. Entamoeba histolytica infections are commonly observed in tropical and subtropical regions of the world including Iran. In developed countries Entamoeba histolytica infections are commonly seen in travelers, recent immigrants, homosexual men, and inmates of institutions. The disease is more severe in the two extremes of life. This paper paper describes a four-month-old male infant with Entamoeba histolytica presenting initially with refusal of feeds, hyperactive bowel sound, vomiting, and diarrhea. A fecal sample was positive for Entamoeba histolytica by Lugol's iodine solution and the concentration technique. He was successfully treated with metronidazole for 5 days. This case illustrates that Entamoebaspecies could be pathogenic in young infant; therefore, awareness of the infection, aggressive approach to diagnosis, and early initiation of treatment continue to be critical com...
The causative agent of intestinal amoebiasis is Entamoeba histolytica (E. histolytica). This parasite is endemic in most tropical and subtropical areas of the world, where it causes millions of cases of dysentery [1 1. S. L. Stanley, “Amoebiasis,” The Lancet, vol. 361, no. 9362, pp. 1025–1034, 2003. View at: Publisher Site| Google Scholar See in References ]. In a national survey of the prevalence of intestinal parasitic infection in Iran, E. histolytica was one of the most common pathogenic protozoa [2 1. A. A. Sayyari, F. Imanzadeh, S. A. Bagheri Yazdi, H. Karami, and M. Yaghoobi, “Prevalence of intestinal parasitic infections in the Islamic Republic of Iran,” Eastern Mediterranean Health Journal, vol. 11, no. 3, pp. 377–383, 2005. View at: Google Scholar See in References ]. In endemic areas, breast-feeding and different socioeconomic status do not protect infants from infection with E. histolytica [3 1. D. Y. Ilikkan, B. Ilikkan, and M. Vural, “Amebiasis in infancy in the middle...
A four-month-old male infant from a rural district in Khorramabad, southwest Iran was brought to the emergency room of the Lorestan University of Medical Sciences Hospital with history of refusal of feeds, hyperactive bowel sound, vomiting, and change in stool texture. The patient also had episodes of retching and mild abdominal distension. The mother suffered abdominal pain and had history of diarrhea. The complete blood count showed a leukocyte count of 7800 μL with eosinophilia of 7%. The results of biochemistry tests were as follows: Na (130.0 mEq/L), Ca (10.4 mg/dL), and total protein (4.6 g/dL) (Table 1). The urine analysis and culture were normal and negative, respectively. Direct examination of fresh fecal samples using Lugol’s iodine solution and the concentration technique showed E. histolytica cysts and trophozoites with red blood cells (occult blood) and many leukocytes (Figure 1). The infant was given metronidazole syrups (35–50 mg/kg/BW/day) and oral rehydration salt (...
Amoebiasis is defined by the World Health Organization (WHO) as infection with Entamoeba histolytica, regardless of symptomatology [5 1. A. Davis and Z. S. Pawlowski, “Amoebiasis and its control,” Bulletin of the World Health Organization, vol. 63, no. 3, pp. 417–426, 1985. View at: Google Scholar See in References , 6 1. WHO/PAHO/UNESCO report, “A consultation with experts on amoebiasis: Mexico City, Mexico 28-29 January,” Epidemiology Bulletin, vol. 18, no. 1, pp. 13–14, 1997. View at: Google Scholar See in References ]. This protozoan parasite is the pathogenic species responsible for amebic colitis throughout the world. It infects people of both sexes and all ages; however, populations at risk may vary with geographic location, host susceptibility, and differences in organism virulence [7 1. J. Blessmann, I. K. M. Ali, P. A. Ton Nu et al., “Longitudinal study of intestinal Entamoeba histolytica infections in asymptomatic adult carriers,” Journal of Clinical Microbiology, vol. 41...
In conclusion, to our knowledge, this is the first reported case of infantile amoebiasis in our area. It draws attention to the possibility of encountering amoebiasis in infant. Such cases should be monitored more closely. An early precise diagnosis is of prime importance because appropriate treatment in addition to supportive care can be life-saving for such patients.
- Mohammad Zibaei, Farzaneh Firoozeh, Alireza Azargoon
Entamoeba histolytica is a cosmopolitan pathogenic parasite. It is spread via the feco-oral route and, to a lesser extent, via sexual intercourse. We report a case of hepatic and intestinal amoebiasis in a 67-year-old man who had never travelled to an endemic area. Abdominal CT investigations detected two liver abscesses and chronic colitis. Positive amoebic serology and a positive PCR test ...
- Anne Claire Billet, Arnaud Salmon Rousseau, Lionel Piroth, Capucine Martins
- Case Report
Entamoeba dispar, a common noninvasive parasite, is indistinguishable in its cysts and trophozoite forms from Entamoeba histolytica, the cause of invasive amebiasis, by microscopy. To differentiate the two species seems to be a problem for laboratory diagnosis. Recent experimental studies showed that E. dispar can be considered pathogenic too. We present a rare case of enteritis due to E. dispar.
Entamoeba histolytica and Entamoeba dispar are two distinct but morphologically identical species living in the human colon [1 1. L. S. Diamond and C. G. Clark, “A redescription of Entamoeba histolytica Schaudinn, 1903 (Emended Walker, 1911) separating it from Entamoeba dispar Brumpt, 1925,” The Journal of Eukaryotic Microbiology, vol. 40, no. 3, pp. 340–344, 1993. View at: Google Scholar See in References , 2 1. R. Haque, I. K. M. Ali, S. Akther, and W. A. Petri Jr., “Comparison of PCR, isoenzyme analysis, and antigen detection for diagnosis of Entamoeba histolytica infection,” Journal of Clinical Microbiology, vol. 36, no. 2, pp. 449–452, 1998. View at: Google Scholar See in References ]. E. histolytica causes amebiasis. Amebiasis is one of the most common causes of death from protozoan parasitic disease, second only to malaria, with approximately 50 million cases and 100 000 deaths annually, as reported by the WHO [3 1. WHO, “Amoebiasis,” The Weekly Epidemiological Record, vol. 7...
An Italian 81-year-old woman suffered of abdominal pain and chronic diarrhea. She evacuated unformed stools three times a day for 10 days. She had not been hospitalized in the last year nor had she traveled to tropical countries. Blood biochemistry and liver function tests were normal, and she was serologically negative for human immunodeficiency virus (HIV). Multiple stool cultures for bacterial pathogens, including Salmonella, Shigella, and Campylobacter, enterotoxigenic and other pathogenic E. coli and C. difficiletoxin A/B were negative. Stools collected for parasites were negative for ova and larvae by microscopy and for Giardia intestinalis and Cryptosporidium parvumby immunochromatographic test (CerTest Biotec S.L. Zaragoza—Spain). Entamoeba histolytica/dispar/moshkovskii cysts were detected by microscopy at wet smear preparation with a 400x phase-contrast objective (Figure 1). Culture was performed in medium based on Boeck and Drbohlav formulation (DiaSys Entamoeba kit, DiaS...
Microscopy is still the gold standard to detect Entamoeba spp. in stool samples, but the use of routine diagnostic methods such as concentration and trichrome staining may be insufficient to demonstrate the presence of E. histolytica/dispar [11 1. L. S. Garcia, R. Y. Shimizu, and C. N. Bernard, “Detection of Giardia lamblia, Entamoeba histolytica/Entamoeba dispar, and Cryptosporidium parvum antigens in human fecal specimens using the triage parasite panel enzyme immunoassay,” Journal of Clinical Microbiology, vol. 38, no. 9, pp. 3337–3340, 2000. View at: Google Scholar See in References ]. Studies about fecal antigen detection for pathogenic E. histolytica provide sensitivities and specificities that range from 87 to 97.6% and 92.6 to 98%, respectively [11 1. L. S. Garcia, R. Y. Shimizu, and C. N. Bernard, “Detection of Giardia lamblia, Entamoeba histolytica/Entamoeba dispar, and Cryptosporidium parvum antigens in human fecal specimens using the triage parasite panel enzyme immunoas...
- Rosalia Graffeo, Carola Maria Archibusacci, Silvia Soldini, Lucio Romano, Luca Masucci
Mar 01, 2020 · A sample of the patient’s blood was sent to the Mayo reference lab for serum Entamoeba histolytica antibody testing, which came back positive. Stool was sent for Entamoeba histolytica antigen testing which was negative. Discussion. Entamoeba coli is a non-pathogenic protozoan that can exist as a commensal organism in the human ...
Entamoeba histolytica is an endoparasite and the parasite inhabits the mucous and sub-mucous layers of the large intestine of man. It may also occur in the liver, lungs and rarely invades brain, spleen, etc. producing ulcers, but the cyst is found in the intestinal lumen of man.