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Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. [1] Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 35-50 million people worldwide. [1] E. histolytica infection is estimated to kill more than 55,000 people each year. [2]
- E. histolytica
- Entamoebidae
- Human
- Entamoeba
Apr 17, 2023 · Entamoeba histolytica is a protozoan that causes intestinal amebiasis as well as extraintestinal manifestations. Although 90 percent of E. histolytica infections are asymptomatic, nearly 50 million people become symptomatic, with about 100,000 deaths yearly.[1] Amebic infections are more prevalent in countries with lower socioeconomic conditions.[2]
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The protozoan parasite Entamoeba histolytica (E. histolytica) is a human pathogen and one of the leading parasitic burdens in developing countries, contributing to an estimated 100,000 deaths annually . E. histolytica spreads by the fecal-oral route mainly in areas where water sanitation is poor . The parasite has a simple two-stage life cycle.
- Laura Morf, Upinder Singh
- 10.1016/j.mib.2012.04.011
- 2012
- 2012/08
Jan 20, 2017 · Entamoeba histolytica ( Eh) is the protozoan parasite responsible for intestinal amebiasis and interacts dynamically with the host intestinal epithelium during disease pathogenesis. A multifaceted pathogenesis profile accounts for why 90% of individuals infected with Eh are largely asymptomatic. For 100 millions individuals that are infected ...
- Steve Cornick, Kris Chadee
- 10.1080/21688370.2017.1283386
- 2017
- Tissue Barriers. 2017; 5(1): e1283386.
May 7, 2020 · Introduction. The protist parasite Entamoeba histolytica causes human amebiasis, a major public health problem in developing countries. Though great strides have been made in understanding the pathobiological mechanisms of the disease in the last few decades, details about the molecular pathways that are involved in tissue invasion and damage during both intestinal and extraintestinal diseases ...
- Mrigya Babuta, Sudha Bhattacharya, Alok Bhattacharya
- 2020
Feb 24, 2005 · Abstract. Entamoeba histolytica is an intestinal parasite and the causative agent of amoebiasis, which is a significant source of morbidity and mortality in developing countries 1. Here we present ...
The mechanism whereby Entamoeba histolytica (Eh) binding with macrophages at the intercellular junction triggers aggressive pro- inflammatory responses in disease pathogenesis is not well understood.
