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  2. Apr 17, 2023 · The pathological range includes mucosal inflammation, thickening, ulcers, and necrosis, leading to perforation. Amoebic cysteine proteinases can also contribute to trophozoites' ability to suppress a host’s immune response by being able to cleave and inactivate anaphylatoxins C3a, C5a, IgA, and IgG. [2]

    • Causal Agents
    • Life Cycle
    • Geographic Distribution

    Several protozoan species in the genus Entamoeba colonize humans, but not all of them are associated with disease. Entamoeba histolytica is well recognized as a pathogenic ameba, associated with intestinal and extraintestinal infections. Other morphologically-identical Entamoeba spp., including E. dispar, E. moshkovskii, and E. bangladeshi, are gen...

    Cysts and trophozoites are passed in feces . Cysts are typically found in formed stool, whereas trophozoites are typically found in diarrheal stool. Infection with Entamoeba histolytica (and E.dispar) occurs via ingestion of mature cysts from fecally contaminated food, water, or hands. Exposure to infectious cysts and trophozoites in fecal matter d...

    Pathogenic Entamoeba species occur worldwide and are frequently recovered from fresh water contaminated with human feces. The majority of amebiasis cases occur in developing countries. In industrialized countries, risk groups include men who have sex with men, travelers, recent immigrants, immunocompromised persons, and institutionalized population...

  3. Amebiasis is a disease caused by a one-celled parasite called Entamoeba histolytica. Who is at risk for amebiasis? Although anyone can have this disease, it is more common in people who live in tropical areas with poor sanitary conditions.

  4. Jun 3, 2020 · Once amoebas invade the tissues, the immune system launches a response against the parasite. In this review, we summarize the current knowledge on the pathogenicity of E. histolytica and on the immune response during amoebiasis. We also discuss some mechanisms used by amoeba to escape the host immune system.

    • Eileen Uribe-Querol, Carlos Rosales
    • 2020
  5. Jul 14, 2014 · Hence, early detection and differentiation of pathogenic E. histolytica from nonpathogenic/commensal Entamoeba spp (Entamoeba dispar/Entamoeba moshkovskii/Entamoeba bangladeshi) plays a crucial role in clinical management of patients with amebiasis.

  6. Nov 12, 2020 · Excystation is the transition from the cyst form to the rapidly dividing trophozoite stage. Once a trophozoite, E. histolytica can either undergo invasive (5% to 10% of symptomatic infections) or noninvasive disease progression.