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Apr 17, 2023 · Entamoeba histolytica is a protozoan that causes intestinal amebiasis as well as extraintestinal manifestations. Although 90 percent of E. histolytica infections are asymptomatic, nearly 50 million people become symptomatic, with about 100,000 deaths yearly.[1] Amebic infections are more prevalent in countries with lower socioeconomic conditions.[2]
Jul 14, 2014 · However, the recent description of various nonpathogenic Entamoeba species like Entamoeba dispar, E. moshkovskii and the newly described Entamoeba bangladeshi as morphologically indistinguishable forms from E. histolytica has required the need for alternative diagnostic methods for differentiation. Since the last decade, molecular methods have ...
- Subhash Chandra Parija, Jharna Mandal, Dinoop Korol Ponnambath
- 2014
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The protozoan parasite Entamoeba histolytica (E. histolytica) is a human pathogen and one of the leading parasitic burdens in developing countries, contributing to an estimated 100,000 deaths annually . E. histolytica spreads by the fecal-oral route mainly in areas where water sanitation is poor . The parasite has a simple two-stage life cycle.
- Laura Morf, Upinder Singh
- 10.1016/j.mib.2012.04.011
- 2012
- 2012/08
- Mode of Transmission
- Life Cycle of Entamoeba histolytica
- Diseases
- Clinical Findings
- Laboratory Diagnosis
Feco-oral route, via the ingestion of contaminated food or water containing mature quadrinucleate cyst of Entamoeba histolytica. Trophozoites if ingested would not surviveexposure to the gastric environment. Infective form: Mature quadrinucleate cyst; it is spherical in shapewith a refractile wall Geographical distribution: Worldwide, more common i...
Infection by Entamoeba histolytica occurs by the ingestion of mature quadrinucleate cysts in fecally contaminated food, water, or hands. The quadrinucleate cyst is resistant to the gastric environmentand passes unaltered through the stomach 1. When the cyst of E.histolytica reaches caecum or lower part of ileum excystation occurs and anamoeba with ...
Non-invasive infection: In many cases, the trophozoites remain confined to the intestinal lumen of individuals who are thus asymptomatic carriers and cysts passers.Intestinal disease: In some patients, the trophozoites invade the intestinal mucosa,Extra-intestinal disease: through the bloodstream, trophozoites invade extraintestinal sites such as the liver, brain, and lungs, with resultant pathologic manifestations.Acute intestinal amebiasisChronic amebiasis: low-grade symptoms such as occasional diarrhea, weight loss, and fatigue also occurs.Roughly 90% of infected individuals have an asymptomatic infection but they may be carriers.Ameboma, a granulomatous lesion may form in the cecal or rectosigmoid areas of the colon in some patients. These lesions resemble an adenocarcinoma of the colon and must be distinguished from them.Diagnosis of intestinal amebiasis rests on finding either trophozoites in diarrheal stools or cysts in formed stools. Diarrheal stools should be examined within one hour of collection to see the ameboid motility of the trophozoite. The trophozoite characteristically contains ingested red blood cells. Characteristics of Stool 1. Macroscopic appearan...
Feb 13, 2017 · Entamoeba histolytica occurs in the following forms, the trophozoites, precyst, cyst, metacyst, and metacystic trophozoite. The trophozoite is about 10–60 μm in size with a clear finely granular cytoplasm and a spherical nucleus that shows aggregation of chromatin beads at the nuclear membrane and a centrally located karyosome.
- Nadia A. El-Dib
- naeldib@hotmail.com
- 2017
Jun 3, 2020 · Entamoeba histolytica is a protozoan parasite responsible for amoebiasis, a disease with a high prevalence in developing countries. Establishing an amoebic infection involves interplay between pathogenic factors for invasion and tissue damage, and immune responses for protecting the host. Here, we review the pathogenicity of E. histolytica and summarize the latest knowledge on immune response ...
Nov 12, 2020 · Entamoeba histolytica is an extracellular enteric eukaryotic parasite. Globally, an average of 50 million cases and 55,000 to 100,000 deaths are due to E. histolytica infection each year, primarily impacting the developing world [ 1, 2 ]. The world is widely unprepared for an outbreak of E. histolytica due to the lack of a vaccine and the use ...
