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  1. What is the Entourage Effect? The theory of the entourage effect was first proposed by Mechoulam and Ben-Shabat who developed a hypothesis that other inactive biological products, accompanying the primary endogenous cannabinoids, increase its activity.

  2. Apr 20, 2017 · This so-called “entourage effect” refers to this scrum of compounds supposedly working in concert to create what Chris Emerson describes as “the sum of all the parts that leads to...

  3. Nov 6, 2018 · Some call it the entourage effect: THC achieves its full effects only when it rolls with a crew of other compounds. Getty Images. Today, cannabis continues its slow march toward...

  4. May 16, 2023 · "The entourage effect is the theory that using a variety of compounds in the cannabis plant is more effective than using any single compound by itself," explains medical cannabis expert and double-board certified doctor Dave Gordon, M.D.

  5. The “entourage effect”, is the suggested positive contribution derived from the addition of terpenes to the effect of cannabinoids (see Fig. 1 1). This means that the entirety of the effect is greater than the sum effects of its contributing parts.

  6. Apr 15, 2024 · The authors noted that this is one of “the first clinical studies that demonstrate the validity of the entourage effect” theory that promotes the idea that the effects of cannabinoids such as THC and CBD can have enhanced medical benefits or mitigated side-effects when combined with terpenes and other cannabinoids naturally occurring within ...

  7. Aug 28, 2019 · 28 August 2019. Cannabis’s chemical synergies. The notion of an ‘entourage effect’ that magnifies the drugs effects is intriguing but lacks solid evidence. By. Tammy Worth. Credit: Susan...

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