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  1. In the United States, a typhus epidemic struck Philadelphia in 1837. The son of Franklin Pierce died in 1843 of a typhus epidemic in Concord, New Hampshire. Several epidemics occurred in Baltimore, Memphis, and Washington, D.C. between 1865 and 1873.

  2. A pair of epidemics struck the Mexican highlands in 1545 and 1576, causing an estimated 7 to 17 million deaths. [19] A study published in 2018 suggests that the cause was typhoid fever. [20][21] Some historians believe that the English colony of Jamestown, Virginia, died out from typhoid.

  3. An epidemic is the rapid spread of disease to a large number of people in a given population within a short period of time; in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic. [1]

    Event
    Years
    Location
    Disease
    1350 BC plague of Megiddo
    c. 1350 BC
    Megiddo, land of Canaan
    Amarna letters EA 244, Biridiya, mayor of ...
    Hittite Plague /"Hand of Nergal"
    c. 1330 BC
    Near East, Hittite Empire, Alashiya, ...
    Unknown, possibly Tularemia. Mentioned in ...
    430–426 BC
    Greece, Libya, Egypt, Ethiopia
    Unknown, possibly typhus, typhoid fever ...
    412 BC
    Greece (Northern Greece, Roman Republic)
    Unknown, possibly influenza
  4. May 15, 2024 · Key points. Epidemic typhus is transmitted through infected body lice. Symptoms of epidemic typhus include fever, headache, rash, and confusion. Symptoms usually begin within two weeks after exposure to infected lice. Treatment for epidemic typhus involves the antibiotic doxycycline.

  5. Jul 19, 2024 · Epidemic Typhus. Epidemic typhus, also called louse-borne typhus, is an uncommon disease caused by bacteria called Rickettsia prowazekii. Epidemic typhus is spread to people through contact with infected body lice.

  6. May 15, 2024 · Key points. The primary vector of epidemic typhus is the human body louse, with transmission occurring through contact with infected lice feces. Epidemic typhus outbreaks are often linked to densely populated environments in situations with limited access to hygienic services. Symptoms include fever, headache, rash, and altered mental status.

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  8. outbreak of epidemic typhus in the 18th century in the context of a pan-European great war in the city of Douai, France, and supported the hypothesis that typhus was imported into Europe by Spanish soldiers returning from America.

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