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  1. Mar 1, 2007 · Erythema nodosum may be the first sign of a systemic disease such as tuberculosis, bacterial or deep fungal infection, sarcoidosis, inflammatory bowel disease, or cancer. Certain drugs,...

  2. www.uptodate.com › contents › erythema-nodosumErythema nodosum - UpToDate

    Mar 9, 2023 · Erythema nodosum (EN) is a delayed-type hypersensitivity reaction that most often presents as erythematous, tender nodules on the shins ( picture 1A-D ). Common triggers for EN include infection, drugs, pregnancy, malignancy, and inflammatory conditions, such as sarcoidosis or gastrointestinal diseases; however, many cases are idiopathic ...

  3. Mar 8, 2021 · Abstract. Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli.

  4. Abstract Number: 613. Category: Clinical Vignettes. Sub-Category: Adult. Keywords: erythema lupus erythematous, erythema nodosum, initial presentation, Lupus, Sle. Case Presentation: A 37-year-old Hispanic female with no medical history presented to the hospital with bilateral lower extremity edema of 3-week duration.

  5. The pathology of erythema nodosum shows inflammation primarily of the septa between the subcutaneous fat lobules without vasculitis [15]. Supporting investigations [4,7] Appropriate tests may include:

  6. Some cases of erythema nodosum are a symptom of an underlying condition, which could include: Ulcerative colitis. Crohn’s disease. Inflammatory bowel disease. Sarcoidosis. Rheumatic fever. Behçet’s disease. Sweet syndrome. Pregnancy. Leukemia. Lymphoma. Side effects of a medication. Erythema nodosum could be a side effect of a medicine you ...

  7. Nov 28, 2022 · Erythema nodosum (EN) is a common acute nodular septal panniculitis, characterized by the sudden onset of erythematous, firm, solid, deep nodules or plaques painful on palpation and mainly localized on extensor surfaces of the legs.

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