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  1. Erythema nodosum is a skin condition that causes a lumpy red rash, usually on your lower legs. It is sometimes caused by an illness, but more than half the time there is no reason found for it. Anyone can get erythema nodosum, but it is most common in females aged 20 to 40 years.

  2. Apr 20, 2023 · The tender lumps, or nodules, of erythema nodosum range in size from one to five centimeters. Inflammation in the fatty layer of skin causes the nodular swelling. Erythema nodosum can be self-limited and resolved on its own in three to six weeks. Upon resolution, it may leave only a temporary bruised appearance or leave a chronic indentation in ...

  3. Jun 29, 2022 · Erythema nodosum is the most common form of panniculitis . However, the condition is rare, affecting up to 5 in 100,000 people. It causes inflammation of the fat tissue in the subcutaneous layer of the skin. Erythema nodosum results in tender lumps or nodules beneath the skin. The nodules appear on both shins, but they can occur in other places.

  4. May 11, 2020 · Tuberculosis was an important cause in the past, but it has decreased dramatically as a cause for erythema nodosum; however, it still must be excluded, especially in developing countries. [ 5 , 6 ] Yersinia enterocolitica is a gram-negative bacillus that causes acute diarrhea and abdominal pain; it is a common cause of erythema nodosum in ...

  5. Erythema nodosum is an inflammatory reaction in the layer of fat under your skin. It causes red or purplish bumps under your skin, often on your shins. Erythema nodosum is most common in people in their 20s and 30s, especially women. It's usually caused by a reaction to a medicine or an infection. In addition to the bumps on your skin, you may ...

  6. Erythema nodosum almost always resolves on its own, and the nodules usually go away in 3 to 6 weeks without treatment. Bed rest, cool compresses, elevation of the legs, and nonsteroidal anti-inflammatory drugs may help relieve the pain caused by the nodules. Potassium iodide tablets may be given to decrease inflammation.

  7. Causes and risk fa ctors for erythema nodosum include infections, medications, pregnancy, cancer, and other inflammatory conditions. Signs and symptoms of erythema nodosum include painful, tender red or purple raised bumps (nodules) on the shins. Other symptoms of EN include joint swelling, redness, or pain, and enlarged lymph nodes in the chest.

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