Search results
Erythromycin's elimination half-life ranges between 1.5 and 2.0 hours and is between 5 and 6 hours in patients with end-stage renal disease. Erythromycin levels peak in the serum 4 hours after dosing; ethylsuccinate peaks 0.5–2.5 hours after dosing, but can be delayed if digested with food.
Jul 2, 2023 · Erythromycin is a macrolide antibiotic initially discovered in 1952. It is useful for treating various infections and also has an indication for a non-infectious pathology.
- 2023/07/02
Apr 20, 2020 · Erythromycin is a macrolide, a type of antibiotic that stops the growth of (or even kills) bacteria by inhibiting bacterial protein production. It’s also a testament to Filipino brilliance… and proof of how corporate interests can trample over the rights of individual thinkers and creators.
Aug 10, 2017 · Since the discovery of the progenitor macrolide, erythromycin, in 1950, many derivatives have been synthesised, leading to compounds with better bioavailability and acid stability and improved pharmacokinetics. These efforts led to the second generation of macrolides, including well‐known members such as azithromycin and clarithromycin.
- George P Dinos
- 10.1111/bph.13936
- 2017
- Br J Pharmacol. 2017 Sep; 174(18): 2967-2983.
Erythromycin has traditionally been used for various respiratory infections (i.e., community-acquired pneumonia, Legionnaires disease), prophylaxis of neonatal conjunctivitis, and chlamydia. It is also FDA-approved for treating skin infections, intestinal amebiasis, rheumatic fever, prophylaxis, syp ….
Dec 31, 2015 · Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others.
Pediatric Dosing. Mild-moderate infections: 30-50 mg/kg/day PO divided q6-8hr. Severe infection: 60-100 mg/kg/day PO divided q6-8hr. Special Populations. Pregnancy Rating: B. Lactation risk: AAP categorizes as compatible with breastfeeding. Renal Dosing: No adjustment. Hepatic Dosing: Use caution. Contraindications. Allergy to class/drug.
