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  1. Aug 6, 2023 · Essential thrombocytosis is characterized by thrombocytosis with the presence of megakaryocytic hyperplasia in the bone marrow. Due to thrombocytosis, there are risks of vascular events such as thrombosis and hemorrhage and sometimes the conversion to a blast phase of myelofibrosis.[4]

  2. Dec 30, 2022 · Overview. Platelets are parts of the blood that help form blood clots. Thrombocytosis (throm-boe-sie-TOE-sis) is a disorder in which your body produces too many platelets. It's called reactive thrombocytosis or secondary thrombocytosis when the cause is an underlying condition, such as an infection.

  3. Essential thrombocythemia is a rare genetic disorder that affects platelets, the blood cells that control bleeding. People with this condition develop many blood clots. This increases their risk of heart attack or stroke. Healthcare providers treat this condition by reducing platelet levels, which reduces the risk of serious complications.

  4. Sep 12, 2022 · Essential thrombocythemia (ET), or primary thrombocytosis, is a rare blood disorder in which your bone marrow makes too many platelets. Your bone marrow makes most of your body’s blood cells, including platelets. With essential thrombocythemia, blood cell production goes wrong, causing you to have abnormal and excess platelets.

  5. Prognosis |. Key Points. |. Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by an increased platelet count, megakaryocytic hyperplasia, and a hemorrhagic or microvascular vasospastic tendency. Symptoms and signs may include headache (ocular migraine), paresthesias, bleeding, erythromelalgia, or digital ischemia.

  6. Essential thrombocythemia is a myeloproliferative neoplasm in which excess platelets are produced, leading to abnormal blood clotting or bleeding. The hands and feet may burn, turn red or discolored, and tingle, and the fingertips may feel cold. Blood tests usually provide a diagnosis, but sometimes a bone marrow biopsy is needed.

  7. Dec 30, 2022 · Essential thrombocythemia. People with this condition who have no signs or symptoms usually don't need treatment. You might need to take daily, low-dose aspirin to help thin your blood if you're at risk of blood clots. Don't take aspirin without checking with your health care team.

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