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   What is FAMMM melanoma?

   • Also called dysplastic nevi syndrome. An inherited condition where a person has many moles (usually more than 50) that often look different than normal moles. A person with FAMMM also has one or more close relatives with melanoma. FAMMM increases the risk of certain cancers, including melanoma skin cancer and pancreatic cancer.

   familial atypical multiple mole melanoma (FAMMM) syndrome

   cancer.ca/en/cancer-information/resources/glossary/f/familial-atypical-multiple-mole-melanoma-fammm-syndrome

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   Does FAMMM cause melanoma?

   • FAMMM increases the risk of certain cancers, including melanoma skin cancer and pancreatic cancer. Also called dysplastic nevi syndrome. An inherited condition where a person has many moles (usually more than 50) that often look different than normal moles. A person with FAMMM also has one or more close relatives with melanoma.

   familial atypical multiple mole melanoma (FAMMM) syndrome

   cancer.ca/en/cancer-information/resources/glossary/f/familial-atypical-multiple-mole-melanoma-fammm-syndrome

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   What is the risk of melanoma in FAMMM syndrome?

   • Melanomas can arise from atypical moles or de novo and have been reported in some FAMMM syndrome patients as early as the second to third decade of life. Those with CDNK2A mutations have a 90% risk of developing melanoma by the age of 80 and a 20% increased risk of developing pancreatic cancer by the age of 75.

   Orphanet: Familial atypical multiple mole melanoma syndrome

   www.orpha.net/en/disease/detail/404560

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2. rarediseases.info.nih.gov › diseases › 9281Familial atypical multiple mole melanoma syndrome

   rarediseases.info.nih.gov › diseases › 9281

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   Familial atypical multiple mole melanoma syndrome (FAMMM syndrome) is an inherited condition characterized by the presence of multiple moles. Atypical moles, also called dysplastic nevi, are benign but are associated with an increased risk of melanoma.

3. rarediseases.oscar.ncsu.edu › disease › familialAbout: Familial atypical multiple mole melanoma syndrome

   rarediseases.oscar.ncsu.edu › disease › familial

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   Familial atypical multiple mole melanoma (FAMMM) syndrome is an inherited genodermatosis characterized by the presence of multiple melanocytic nevi (often >50) and a family history of melanoma as well as, in a subset of patients, an increased risk of developing pancreatic cancer (see this term) and other malignancies. Go To Source: Orphanet.

4. www.orpha.net › en › diseaseOrphanet: Familial atypical multiple mole melanoma syndrome

   www.orpha.net › en › disease

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   Disease definition. Familial atypical multiple mole melanoma (FAMMM) syndrome is an inherited genodermatosis characterized by the presence of multiple melanocytic nevi (often >50) and a family history of melanoma as well as, in a subset of patients, an increased risk of developing pancreatic cancer (see this term) and other malignancies.

5. www.jaad.org › article › S0190-9622(15)02108-8Hereditary melanoma: Update on syndromes and management

   www.jaad.org › article › S0190-9622(15)02108-8

   In the past few years, melanomas have also been found to arise in families that are generally prone to specific patterns of malignancies. The term melanoma tumor syndrome might be more appropriate to discriminate it from hereditary melanoma, where the dominant cancer phenotype is that of CMM.

   • Author: Efthymia Soura, Philip J. Eliades, Kristen Shannon, Alexander J. Stratigos, Hensin Tsao

   • Publish Year: 2016

6. link.springer.com › chapter › 10Familial Atypical Mole Melanoma (FAMM) Syndrome | SpringerLink

   link.springer.com › chapter › 10

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   Jan 1, 2010 · The familial atypical mole-melanoma (FAMM) syndrome is a form of hereditary melanoma that can be recognized by the presence of a strong familial predisposition to cutaneous melanoma and by large numbers of clinically and pathologically confirmed atypical nevi.

   • Author: Elizabeth D. Chao, Michele J. Gabree, Hensin Tsao

   • Publish Year: 2010

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8. www.visualdx.com › visualdx › diagnosisFamilial atypical multiple mole-melanoma syndrome - VisualDx

   www.visualdx.com › visualdx › diagnosis

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   Aug 15, 2021 · Familial atypical multiple mole-melanoma (FAMMM) syndrome is an autosomal dominantly inherited melanoma predisposition syndrome in which germline CDKN2A mutations (and much less commonly CDK4 mutations) lead to a predisposition to melanoma and atypical moles, as well as pancreatic cancer in some kindreds.

9. cancer.ca › en › cancer-informationfamilial atypical multiple mole melanoma (FAMMM) syndrome

   cancer.ca › en › cancer-information

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   FAMMM increases the risk of certain cancers, including melanoma skin cancer and pancreatic cancer. Also called dysplastic nevi syndrome. An inherited condition where a person has many moles (usually more than 50) that often look different than normal moles.