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Fixed drug eruption. FDEs occur as an allergic reaction to drug exposure and appear as round, dark spots on the skin. Pain and burning can sometimes be associated with the spots. Image Source: ISM / Medical Images. Text Source: QxMD Medline. View an Illustration of Fixed Drug Eruption and learn more about Papules, Scales, Plaques and Eruptions.
Feb 12, 2019 · A drug rash or other reaction may occur for several reasons, such as: an allergic reaction. a buildup of the drug that causes toxicity to the skin. a drug makes the skin more sensitive to sunlight ...
Aug 8, 2022 · Although patch testing was negative, an oral rechallenge with 100 mg doxycycline was positive. Fixed drug eruptions are common, 1, 2 and constitute 14%–22% of cutaneous drug reactions among children. 3 They are type IV hypersensitivity reactions that appear within 1 week after initial drug exposure, but may occur within minutes upon re ...
May 23, 2022 · INTRODUCTION. Fixed drug eruption (FDE) is a distinctive type of cutaneous drug reaction that characteristically recurs in the same locations upon re-exposure to the offending drug. Acute FDE usually presents with a single or a small number of dusky red or violaceous plaques that resolve leaving postinflammatory hyperpigmentation ( picture 1A-C ).
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Introduction. A fixed-drug eruption (FDE) is an immunological cutaneous adverse reaction characterized by sharply defined lichenoid lesion/s which occur/s at the same location every time there is exposure to the causative substance. [ 1] Exogenous agents are the only known cause of FDE.
Aug 11, 2011 · Fixed drug eruption. Images in clinical medicine. Fixed drug eruption. N Engl J Med. 2011 Aug 11;365 (6):e12. doi: 10.1056/NEJMicm1013871.
