Search results
Apr 8, 2024 · Fixed drug eruption (FDE) is a distinctive type of cutaneous drug reaction that characteristically recurs in the same locations upon re-exposure to the offending drug. Acute FDE usually presents with a single or a small number of dusky red or violaceous plaques that resolve leaving postinflammatory hyperpigmentation ( picture 1A-C ).
What is the treatment for fixed drug eruption? Discontinuation of suspected medication; Avoiding implicated medication indefinitely; Topical steroids/ systemic corticosteroids; Generalised bullous fixed drug eruption requires intensive care or burns unit; What is the outcome for fixed drug eruption?
Sep 1, 2021 · Fixed drug eruption (FDE) is a cutaneous adverse drug reaction characterized by the onset of rash at a fixed location on the body each time a specific medication is ingested. With each recurrence, the eruption can involve additional sites.
Feb 22, 2023 · Exanthematous (maculopapular) drug eruption; Fixed drug eruption; Hand-foot skin reaction induced by multitargeted tyrosine kinase inhibitors; Hypersensitivity reactions to clopidogrel; Hypersensitivity reactions to fluoroquinolones; Hypersensitivity reactions to insulins
Treatment of localized FDE includes medication removal, patient counseling, and symptomatic relief. Failure to remove the causative agent in localized FDE can lead to recurrence, which is associated with increased inflammation, hyperpigmentation, and risk of a potentially lethal generalized bullous FDE (GBFDE), which may resemble Stevens ...
The main goal of treatment is to identify the causative agent and avoid it. Treatment for fixed drug eruptions (FDEs) otherwise is symptomatic. Systemic antihistamines and topical...
Jan 30, 2020 · Article 17 July 2021. Key Points. A fixed drug eruption (FDE) is a common drug eruption with distinctive morphology and etiology that ranges from antibiotics to cryptic exposure such as to quinine in a gin and tonic. Generalized bullous FDE may resemble SJS/TEN and may prove to be as deadly.
